Evidence map›Paper›PMID 40382533›Full record

ArticleBMC pregnancy and childbirth2025

Individualized intervention and growth dynamics assessment in TRAP sequence with conjoined twins based on radiofrequency ablation.

Hua Lai, Huiting Zhu, Jinliang Zhang, Juhua Xiao, Mengjiao Liu, Danping Liu, Zengming Li, Xin Zhou

Abstract readCase Reports
In one paragraph

Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hua Lai *Department of Obstetrics, Jiangxi Maternal and Child Health Hospital, Nanchang, 330006, China.
Huiting Zhu *Department of Obstetrics, Jiangxi Maternal and Child Health Hospital, Nanchang, 330006, China.
Jinliang ZhangDepartment of Obstetrics, Jiangxi Maternal and Child Health Hospital, Nanchang, 330006, China.
Juhua XiaoDepartment of Ultrasound, Jiangxi Maternal and Child Health Hospital, 508 Xizhan Avenue, Nanchang, Jiangxi, 330006, China.
Mengjiao LiuJiangxi Provincial Key Laboratory of Preventive Medicine, Nanchang University, Jiangxi, China.
Danping LiuDepartment of Genetics, Jiangxi Maternal and Child Health Hospital, Nanchang, 330006, China.
Zengming LiJiangxi Key Laboratory of Reproductive Health, 508 Xizhan Avenue, Nanchang, Jiangxi, 330006, China. lizengming0707@163.com.
Xin ZhouDepartment of Ultrasound, Jiangxi Maternal and Child Health Hospital, 508 Xizhan Avenue, Nanchang, Jiangxi, 330006, China. jxsfbcsk@163.com.

Funding

Science and Technology Plan of Jiangxi Provincial Health Commission 202110093Science and Technology Project of Jiangxi Province 20212BAG70006 and 20242BAB25447
6 · The paper itself

Abstract

backgroundTwin reversed arterial perfusion (TRAP) sequence with conjoined twins (CTs) represents an exceedingly rare and critical complication in monochorionic monoamniotic (MCMA) twin pregnancies. High mortality rates are associated with this condition, making early diagnosis and management crucial for improving survival outcomes, particularly for the pump twin. CASE PRESENTATION: This case report focuses on a unique instance of TRAP-associated CTs, diagnosed at 13 weeks and 1 day of gestation. Management involved detailed ultrasonography and radiofrequency ablation (RFA) at 18 weeks and 5 days to interrupt the blood supply to the non-viable acardiac twin. This intervention allowed the pump twin to continue normal development, culminating in a cesarean delivery at 35 weeks and 1 day. The newborn showed a healthy postnatal outcome with no significant neurodevelopmental deficits noted at follow-up.

conclusionsEarly identification and tailored intervention are essential in cases of TRAP sequence associated with conjoined twins. This case exemplifies the potential of integrated multidisciplinary approaches and timely use of RFA, which significantly enhance the prognosis for the viable twin. These strategies are vital for managing complex MCMA pregnancies and can inform future clinical practices.

Indexed as

Fetofetal TransfusionRadiofrequency AblationTwins, ConjoinedAdultCesarean SectionFemaleHumansInfant, NewbornPregnancyPregnancy, TwinTwins, MonozygoticUltrasonography, PrenatalConjoined twinsFetal growth curveMonochorionic monoamnioticPerinatal managementRadiofrequency ablationTwin reversed arterial perfusion

Identifiers

PMID40382533
PMCPMC12085842

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.