Evidence map›Paper›PMID 40382345›Full record

ArticleCell death discovery2025

METTL13 is essential for the survival of acute myeloid leukemia cells by regulating MYC.

Kui Zhao, Hanyue Zhang, Shuoting Wang, Yuhang Zhou, Zhishuai Zhang, Baoqiang Kang, Huaisong Lin, Yanqi Zhang, Jiaming Gu, Carla Pantoja and 5 more

Abstract read
In one paragraph

Article in Cell death discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kui Zhao *Department of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, 510630, Guangzhou, China.ORCID http://orcid.org/0000-0001-9338-6675
Hanyue Zhang *Department of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, 510630, Guangzhou, China.
Shuoting Wang *Department of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, 510630, Guangzhou, China.
Yuhang ZhouDepartment of Gastroenterology, The Eighth Affiliated Hospital, Sun Yat-sen University, 518033, Shenzhen, China.
Zhishuai ZhangGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530, Guangzhou, China.
Baoqiang KangGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530, Guangzhou, China.
Huaisong LinGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530, Guangzhou, China.
Yanqi ZhangGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530, Guangzhou, China.ORCID http://orcid.org/0000-0001-6896-8657
Jiaming GuGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530, Guangzhou, China.ORCID http://orcid.org/0000-0002-1612-6711
Carla PantojaDepartment of Cell Biology, Yale University, New Haven, CT, USA.
Lingling LiuDepartment of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, 510630, Guangzhou, China.
Yi HeDepartment of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, 510630, Guangzhou, China.
Guangjin PanGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530, Guangzhou, China. pan_guangjin@gibh.ac.cn.ORCID http://orcid.org/0000-0002-2378-7198
Yongli ShanGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530, Guangzhou, China. shan_yongli@gibh.ac.cn.ORCID http://orcid.org/0000-0001-7018-6478
Bing LongDepartment of Hematology, The Third Affiliated Hospital, Sun Yat-sen University, 510630, Guangzhou, China. longb3@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0001-7309-3736

Funding

IMMUNOHEMATOLOGY/TRANSFUSION MEDICINE RESEARCH TRAININGT32HL007974 · NHLBI · YALE UNIVERSITY · PI JEANNE E HENDRICKSON, Diane S Krause · 2001 to 2026
$8.1M
National Natural Science Foundation of China (National Science Foundation of China) 81700149National Natural Science Foundation of China (National Science Foundation of China) 82103098NHLBI NIH HHS T32 HL007974
6 · The paper itself

Abstract

Recently, some methyltransferase-like (METTL) proteins have been found to play crucial roles in the development of acute myeloid leukemia (AML) through mediating RNA modifications, such as METTL3/14/16 mediated N

Identifiers

PMID40382345
PMCPMC12085568

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.