Evidence map›Paper›PMID 40381493›Full record

ArticleJournal of anxiety disorders2025

Who defines improvement? Patients' global reports of improvement compared to standardized measures of improvement in cognitive processing therapy for posttraumatic stress disorder.

Elizabeth Alpert, Annie B Fox, Tara E Galovski

Abstract readComparative Study
In one paragraph

Article in Journal of anxiety disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth AlpertNational Center for PTSD Women's Health Sciences Division at VA Boston Healthcare System, Boston, MA, USA; Boston University Chobanian & Avedisian School of Medicine Department of Psychiatry, Boston, MA, USA. Electronic address: Elizabeth.Alpert@va.gov.
Annie B FoxNational Center for PTSD Women's Health Sciences Division at VA Boston Healthcare System, Boston, MA, USA; School of Healthcare Leadership, MGH Institute of Health Professions, Boston, MA, USA.
Tara E GalovskiNational Center for PTSD Women's Health Sciences Division at VA Boston Healthcare System, Boston, MA, USA; Boston University Chobanian & Avedisian School of Medicine Department of Psychiatry, Boston, MA, USA.

Funding

Improving Effectiveness: Treatment Outcome ResearchR34MH074937 · NIMH · UNIVERSITY OF MISSOURI-ST. LOUIS · PI GALOVSKI, TARA E · 2007 to 2009
$612k
Sleep-directed hypnosis as a complement to CPT in treating PTSDR21AT004079 · NCCIH · UNIVERSITY OF MISSOURI-ST. LOUIS · PI GALOVSKI, TARA E · 2008 to 2010
$602k
Enhancing PTSD Treatment Outcomes by Improving Patient-Provider CommunicationK23MH132815 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Elizabeth Rose Alpert · 2024 to 2026
$566k
NCCIH NIH HHS R21 AT004079NIMH NIH HHS K23 MH132815NIMH NIH HHS R34 MH074937
6 · The paper itself

Abstract

Standardized measures have typically been used to assess symptom change during treatment in psychological research and practice. However, standardized measures may not fully capture patients' experiences of therapeutic change. Patients' global reports of their improvement during treatment across domains of symptoms and functioning are also important and may provide distinct information from standardized measures. The current study compared both types of patient reports of improvement during cognitive processing therapy (CPT) for posttraumatic stress disorder (PTSD). We also examined process-level predictors of improvement assessed using both methods. Participants were 254 adult survivors of interpersonal violence receiving CPT. Patients' global reports of improvement in each domain (PTSD symptoms, relationships, health concerns, sexual functioning, school/work performance, and life satisfaction), each rated on a Likert scale via the Treatment Outcome Questionnaire, were significantly correlated with the corresponding standardized measure of improvement in the same domain, with most effect sizes in the small-to-medium range. Patients' perceptions of the therapy (helpfulness, likability) significantly predicted both global ratings and standardized measures of improvement, while patients' perceptions of the therapeutic relationship, patients' perceptions of barriers to therapy attendance, and objective indices of attendance did not predict improvement. Results highlight the importance of patients' experiences with treatment and suggest that assessing patients' global ratings of their improvement during treatment provides distinct information from standardized measures of improvement, and both are important to include when measuring therapeutic change.

Indexed as

Cognitive Behavioral TherapyPatient SatisfactionStress Disorders, Post-TraumaticAdultFemaleHumansMaleMiddle AgedSurveys and QuestionnairesTreatment OutcomeYoung AdultMeasurementNonspecific factorsPosttraumatic stress disorderTrauma-focused treatmentTreatment process

Identifiers

PMID40381493
PMCPMC12147656

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.