Evidence map›Paper›PMID 40381207›Full record

ArticleRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)2025

Can socioeconomic status moderate the effect of a conflictive family environment on brain structure and externalizing/internalizing behavior in children and adolescents?

Elizabeth Trejos-Castillo, Ann Mastergeorge, Hugo Cogo-Moreira, Vinicius Oliveira Santana, André Zugman, Célia Maria de Araújo, Pedro Mario Pan, Felipe Picon, Luis Augusto Paim Rohde, Andrea P Jackowski

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Article in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Elizabeth Trejos-CastilloHuman Development & Family Sciences, Texas Tech University, Lubbock, Texas, USA.
Ann MastergeorgeHuman Development & Family Sciences, Texas Tech University, Lubbock, Texas, USA.
Hugo Cogo-MoreiraDepartment of Education, Information and Communications Technology and Learning, Østfold University College, Halden, Norway.
Vinicius Oliveira SantanaLaboratório Interdisciplinar de Neurociências Clínicas, Departamento de Psiquiatria, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
André ZugmanLaboratório Interdisciplinar de Neurociências Clínicas, Departamento de Psiquiatria, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Célia Maria de AraújoLaboratório Interdisciplinar de Neurociências Clínicas, Departamento de Psiquiatria, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Pedro Mario PanLaboratório Interdisciplinar de Neurociências Clínicas, Departamento de Psiquiatria, Universidade Federal de São Paulo, São Paulo, SP, Brazil. Instituto Nacional de Ciência e Tecnologia de Psiquiatria do Desenvolvimento para a Infância e Adolescê ncia, São Paulo, SP, Brazil.
Felipe PiconInstituto Nacional de Ciência e Tecnologia de Psiquiatria do Desenvolvimento para a Infância e Adolescê ncia, São Paulo, SP, Brazil. Programa de Déficit de Atenção/Hiperatividade, Divisão Adulto, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil. Departamento de Psiquiatria, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Luis Augusto Paim RohdeInstituto Nacional de Ciência e Tecnologia de Psiquiatria do Desenvolvimento para a Infância e Adolescê ncia, São Paulo, SP, Brazil. Programa de Déficit de Atenção/Hiperatividade, Divisão Adulto, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil. Departamento de Psiquiatria, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Andrea P JackowskiLaboratório Interdisciplinar de Neurociências Clínicas, Departamento de Psiquiatria, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 15/50469-0
6 · The paper itself

Abstract

objectiveThis study examined the effects of socioeconomic status as a possible moderator of the effects of family conflict on externalizing/internalizing behavior and hippocampal and amygdala volume.

methodsA longitudinal complete-case analysis of 714 children and adolescents (mean age: 11.2 years; 46.2% female) was conducted using data from the Brazilian High-Risk Cohort Study for Psychiatric Disorders in Childhood. At baseline, parents/guardians completed the Family Environment Scale and a socioeconomic status scale. Three years after baseline assessment, the same participants underwent brain magnetic resonance imaging, and the Child Behavior Checklist was administered. Automated segmentation of the amygdala and hippocampus was performed in FreeSurfer 5.1.

resultsAlthough family conflict at baseline predicted externalizing/internalizing behavior at follow-up, we found no evidence that family conflict and socioeconomic status affected brain structure or that family conflict had a moderating effect on psychopathology and brain outcomes conditioned on socioeconomic status.

conclusionThese results are consistent with emerging evidence that family conflict is a risk factor for externalizing/internalizing behavior in youth. These findings warrant further attention, focusing on prevention and intervention efforts and social policy development.

Indexed as

AmygdalaBrainChild BehaviorChild Behavior DisordersFamily ConflictHippocampusSocial ClassAdolescentBrazilChildFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleRisk Factorsbrain structureChild behaviourfamily conflictsocioeconomic status

Identifiers

PMID40381207
PMCPMC12815386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.