Evidence map›Paper›PMID 40381166›Full record

ArticleMolecular neurobiology2025

Analgesic Effects of Acupressure on Jing-jiaji Acupoints in a Rat Model of Cervical Spondylotic Radiculopathy.

Shang-Hong Jiang, Song Yang, Ling Meng, Ling-Yao Xie, Jia-Ni Yang, Si-Qi Li, Ke-Ying Liao, Zhi-Fang Qiu, Yao-Yao Xiao, Man-Di Fu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shang-Hong JiangHunan University of Traditional Chinese Medicine, Changsha, 410000, Hunan Province, China.
Song YangAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Ling MengAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Ling-Yao XieAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Jia-Ni YangAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Si-Qi LiAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Ke-Ying LiaoAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Zhi-Fang QiuAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Yao-Yao XiaoAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Man-Di FuAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China.
Zhi-Li LiuAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China. pangliaobo9737@163.com.
Xue-Yu JiangAcupuncture Department I, Yueyang Hospital of Traditional Chinese Medicine, Yueyang, 414000, Hunan Province, China. j_xueyu@126.com.

Funding

General Issues of Hunan Provincial Health Commission D202304079413Program from Ministry of Science and Technology 2018YFC1707800The General Program of Natural Science Foundation of Hunan Province, China 2019JJ40217
6 · The paper itself

Abstract

backgroundCervical spondylotic radiculopathy (CSR) is increasingly prevalent, causing neck pain and radiating symptoms. As alternatives to surgery, acupressure stimulation of Jing-jiaji acupoints therapies have gained traction albeit lacking evidence.

methodsRats underwent spinal cord compression modeling CSR or sham surgery, alongside normal controls. A week post-surgery, CSR rats underwent no intervention or standardized acupressure of Jing-jiaji acupoints at 2, 4 or 6N. Sensory, locomotor and electrophysiological functions were assessed along with tissue analyses for pain mediators.

resultsRelative to sham group, untreated CSR rats exhibited mechanical/pressure pain hypersensitivity, gait impairments, slowed nerve conduction velocities and reduced sensory evoked potentials, accompanied by heightened spinal inflammation and neuronal damage. Acupressure markedly attenuated these neuropathic CSR manifestations in a stimulus-dependent manner, with maximal therapeutic efficacy observed at 4-6N intensity.

conclusionThis study demonstrates bilateral acupressure stimulation of neck Jing-jiaji acupoints to effectively mitigate characteristic neurogenic pain and neurological dysfunction in a rodent CSR model.

Indexed as

AcupressureAcupuncture PointsRadiculopathySpondylosisAnimalsDisease Models, AnimalMaleRatsRats, Sprague-DawleyAcupressureCervical spondylotic radiculopathyJing-jiaji acupointsNeuropathic painPPAR-γ

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.