Evidence map›Paper›PMID 40381072›Full record

ArticleBiotechnology letters2025

Improvement of transglutaminase production by controlling the morphology of Streptomyces mobaraensis HVCP-Sm1 with microparticle-enhanced cultivation.

Ting-Ting Chang, Lu-Yao Bian, Chong Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Biotechnology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Energy metabolism reprogramming in Streptomyces mobaraensis driven by microparticles enhances transglutaminase production.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ting-Ting ChangLaboratory of Food Industrial Enzyme Technology, College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China.
Lu-Yao BianLaboratory of Food Industrial Enzyme Technology, College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China.
Chong ZhangLaboratory of Food Industrial Enzyme Technology, College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China. zhangchong@njau.edu.cn.ORCID http://orcid.org/0000-0002-7916-5136

Funding

Taixing Dongsheng Biotechnology Co., Ltd HM0055
6 · The paper itself

Abstract

objectiveTransglutaminase (TGase) is widely utilized in food, textile, and medical applications due to its superior capacity to facilitate protein cross-linking. The mechanisms driving high TGase production in Streptomyces mobaraensis require further exploration. "Microparticle-Enhanced Cultivation" (MPEC), has been shown to significantly influence the morphology of filamentous microorganisms, thereby impacting secondary metabolism.

resultIn the study, CaCO

conclusionThe synergistic effects of group sensing, energy metabolism, and the optimization of mycelial morphology enhanced the secondary metabolism of HVCP-Sm1 and increased TGase enzymatic activity.

Indexed as

Bacterial ProteinsStreptomycesTransglutaminasesCalcium CarbonateSecondary MetabolismBacterial ProteinsCalcium CarbonateTransglutaminasesCaCO3Hyphal particlesMicroparticle-enhanced cultivationTalcTransglutaminase

Identifiers

PMID40381072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.