Evidence map›Paper›PMID 40381046›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Efficacy of compression therapy for prevention of peripheral neuropathy caused by taxane-based chemotherapy: a single-center retrospective observational study.

Yuko Kanbayashi, Takeshi Ishikawa, Yusuke Tabuchi, Kazuko Sugatani, Tetsuya Taguchi, Koichi Takayama

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Compression therapy for taxane-induced peripheral neuropathy: promising results undermined by methodological gaps.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yuko KanbayashiDepartment of Outpatient Oncology Unit, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan. yuko.kambayashi@ompu.ac.jp.
Takeshi IshikawaDepartment of Outpatient Oncology Unit, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yusuke TabuchiDepartment of Outpatient Oncology Unit, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kazuko SugataniDepartment of Outpatient Oncology Unit, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tetsuya TaguchiDepartment of Endocrine and Breast Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Koichi TakayamaDepartment of Outpatient Oncology Unit, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChemotherapy-induced peripheral neuropathy (CIPN) is a significant complication of taxane-based chemotherapies that limits their clinical utility. This study evaluated the effectiveness of compression therapy using surgical gloves in preventing CIPN in various cancer types, including, but not limited to, breast cancer. PATIENTS AND

methodsData from 603 patients who underwent taxane-based chemotherapy at a single institution between April 2018 and January 2024 were retrospectively analyzed. Variables associated with CIPN development were extracted and analyzed using uni- and multivariate ordered logistic regression models.

resultCompression therapy was significantly associated with a reduced incidence of CIPN. Significant predictors of CIPN included lung cancer (odds ratio [OR] = 0.342, P = 0.003), number of chemotherapy cycles (OR = 1.015, P = 0.033), and use of surgical gloves (OR = 0.559, P = 0.003).

conclusionCompression therapy using simple, cost-effective surgical gloves appeared effective for preventing CIPN in a diverse cancer population undergoing taxane-based chemotherapy. The risk of CIPN increases with the number of chemotherapy cycles, and a lower incidence was observed among patients with lung cancer. These findings provide a foundation for future research aimed at improving patient quality of life during taxane-based chemotherapy.

Indexed as

Antineoplastic AgentsPeripheral Nervous System DiseasesTaxoidsAdultAgedAged, 80 and overBreast NeoplasmsBridged-Ring CompoundsFemaleHumansMaleMiddle AgedNeoplasmsRetrospective StudiesAntineoplastic AgentsBridged-Ring CompoundstaxaneTaxoidsCancer supportive careCIPNCompression therapySurgical glovesTaxane-based chemotherapy

Identifiers

PMID40381046

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.