ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025
Analysis of risk factors affecting lumbosacral pseudoarthrosis in multi-segmental fusion: a CT-based study.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- The Impact of Proton Pump Inhibitors on Pseudarthrosis Rates Following Multi-Level Lumbar Fusion.Spine surgery and related research · 2026Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to evaluate factors influencing the occurrence of pseudoarthrosis in L5-S1 fusion during long-level fusion.
methodsA retrospective analysis was conducted on 88 patients who underwent L5-S1 interbody fusion with minimum 2 years of follow up. The fusion status of the lumbosacral joint was evaluated using computed tomography of postoperative two year and patients were divided into union and nonunion group. The study assessed sagittal parameters, clinical outcomes, and radiological findings. Univariate and multivariate analyses were employed to identify predictors of pseudoarthrosis in lumbosacral joint.
resultsAmong 88 patients, 70 achieved union, while 18 (20.5%) had pseudoarthrosis. Multivariate analysis identified male gender and prior fusion in other segments as nonunion predictors (p = 0.034, OR = 3.665; p = 0.045, OR = 3.099, respectively). S1 screw loosening was significantly higher in the nonunion group (p = 0.002).
conclusionInterbody fusion at the lumbosacral joint demonstrates a relatively high rate of nonunion, especially in males and patients with prior fusion in other segments. Caution is warranted in performing interbody fusion at the lumbosacral joint in such cases due to an elevated risk of nonunion. Loosening of S1 screw warrants careful consideration to prevent pseudoarthrosis.
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