Evidence map›Paper›PMID 40380953›Full record

ArticleJournal of medicinal chemistry2025

Fluorescent 4-Nitrobenzo-2-oxa-1,3-diazole-Coupled Bile Acids as Probe Substrates of Hepatic and Intestinal Bile Acid Transporters of the Solute Carrier Families SLC10 and SLCO.

Celine Drossel, Sebastian Kunz, Christopher Neelen, Mats Georg, Yohannes Hagos, Dieter Glebe, Richard Göttlich, Joachim Geyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Celine DrosselInstitute of Organic Chemistry, Justus Liebig University Giessen, Heinrich-Buff-Ring 17, Giessen 35392, Germany.ORCID 0009-0005-0111-2324
Sebastian KunzInstitute of Pharmacology and Toxicology, Justus Liebig University Giessen, Schubertstr. 81, Giessen 35392, Germany.
Christopher NeelenInstitute of Pharmacology and Toxicology, Justus Liebig University Giessen, Schubertstr. 81, Giessen 35392, Germany.
Mats GeorgInstitute of Organic Chemistry, Justus Liebig University Giessen, Heinrich-Buff-Ring 17, Giessen 35392, Germany.
Yohannes HagosPortaCellTec Biosciences GmbH, Science Park Va, Marie-Curie-Strasse 8, Göttingen 37079, Germany.
Dieter GlebeNational Reference Centre for Hepatitis B viruses and Hepatitis D viruses, German Center for Infection Research (DZIF), Institute of Medical Virology, Justus Liebig University of Giessen, partner site Giessen-Marburg-Langen, Schubertstr. 81, Giessen 35392, Germany.
Richard GöttlichInstitute of Organic Chemistry, Justus Liebig University Giessen, Heinrich-Buff-Ring 17, Giessen 35392, Germany.
Joachim GeyerInstitute of Pharmacology and Toxicology, Justus Liebig University Giessen, Schubertstr. 81, Giessen 35392, Germany.ORCID 0000-0003-2663-1858

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several bile acid (BA) transporters are involved in the enterohepatic BA circulation between the liver and gut, including the hepatic Na

Indexed as

Bile Acids and SaltsFluorescent DyesLiverOrganic Anion TransportersOrganic Anion Transporters, Sodium-DependentOxadiazolesSymporters4-Chloro-7-nitrobenzofurazanAnimalsHEK293 CellsHumansIntestinal MucosaMicePeptides4-Chloro-7-nitrobenzofurazanBile Acids and SaltsFluorescent DyesOrganic Anion TransportersOrganic Anion Transporters, Sodium-DependentOxadiazolesPeptidessodium-bile acid cotransporterSymporters

Identifiers

PMID40380953
PMCPMC12169615

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.