Evidence map›Paper›PMID 40380244›Full record

ReviewJournal of orthopaedic surgery and research2025

Natural traditional Chinese medicine products: emerging therapeutic targets for the treatment of osteoporosis.

Bo Liu, Xue Mao, Zhe-Jian-Yi Gao, Huan Wang

Abstract readReview
In one paragraph

Review in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Stem cells international · 2026
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bo Liu *Department of Orthopedics, The Fourth People's Hospital of Shenyang, 20 Huanghe Dajie, Huanggu District, Shenyang, 110031, Liaoning, China.
Xue Mao *Department of Orthopedics, Fushun Hospital of Chinese Medicine, No.9, East 6 th Road, Zhanqian Street, Xinfu District, Fushun, 113000, Liaoning, China.
Zhe-Jian-Yi GaoDepartment of Orthopedics, Fushun Hospital of Chinese Medicine, No.9, East 6 th Road, Zhanqian Street, Xinfu District, Fushun, 113000, Liaoning, China. gao_zhe_jian_yi@outlook.com.
Huan WangDepartment of Orthopedics, Liaoning University of Traditional Chinese Medicine, 79 Chongshan Road, Huanggu District, Shenyang, 110847, Liaoning, China. wang6688happy@21cn.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a systemic metabolic degenerative bone disease characterised by decreased bone mass, impaired bone microstructure, weakened bone strength and susceptibility to fracture. In China, the prevention and treatment of osteoporosis is faced with a high disease prevalence rate but low awareness, diagnosis and treatment rates. Bone resorption inhibitors and bone formation promoters often dominate osteoporosis treatment. Although conventional drugs can alleviate symptoms and reduce fracture risk, they often come with musculoskeletal, allergic and digestive side effects. Natural traditional Chinese medicine (TCM) products, known for their multi-targeting, high safety, efficacy and low cost, have been widely used in the treatment and prevention of osteoporosis in recent years and have gradually been recognised by many experts locally and abroad. This paper summarises recent research progress on natural TCM products in preventing and treating osteoporosis and provides a theoretical and experimental basis for the development of new drugs and the improvement of osteoporosis management.

Indexed as

Biological ProductsBone Density Conservation AgentsDrugs, Chinese HerbalMedicine, Chinese TraditionalOsteoporosisAnimalsHumansBiological ProductsBone Density Conservation AgentsDrugs, Chinese HerbalNatural productsOsteoblastOsteoclastOsteoporosisTraditional Chinese medicine

Identifiers

PMID40380244
PMCPMC12083174

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.