Evidence map›Paper›PMID 40380213›Full record

ArticleJournal of orthopaedic surgery and research2025

Evaluation of internal fixation stability of distal humerus C-type fractures based on musculoskeletal dynamics: finite element analysis under dynamic loading.

Zhengfeng Jia, Cheng Xu, Weilu Gao, Changsen Yang, Peifu Tang, Jiantao Li

Abstract read
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Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Internal Density Calibration in the Proximal Humerus to Estimate Bone Stiffness for Stemless Shoulder Arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
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5 · Who and what money

Authors and funding

6 authors.

Zhengfeng Jia *Senior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China.
Cheng Xu *Senior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China.
Weilu Gao *Senior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China.
Changsen YangSenior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China.
Peifu TangSenior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China. pftang301@126.com.
Jiantao LiSenior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, China. lijiantao618@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study establishes a quantitative anatomical-mechanical-clinical decision-making mapping relationship using the Digital Intelligence Orthopaedic Technology, systematically analyses the dynamic biomechanical characteristics of distal humerus fracture in the postoperative period, and establishes the quantitative correlation between optimal strategies of plate configuration and safety thresholds for joint activities, to provide the scientific basis for optimizing internal fixation schemes and quantifying postoperative rehabilitation strategies.

methodsUpper limb muscle modeling was carried out in AnyBody software, muscle force, and other data were exported for finite distance solving and dynamic mechanical conditions were exported as the database for dynamic loading. Coupling the musculoskeletal dynamics simulation with finite element calculation, the elbow flexion-extension angle-muscle force-inner fixation stress transfer chain was established by AnyBody-Abaqus joint modeling technique to quantify the dynamic thresholds of the interface fracture micromovement (IFM) under different activity angles. The effects of different plate configurations (parallel plate, posterior medial plate, posterior lateral plate) on fracture stability and early healing were analyzed.

resultsIn this study, we systematically evaluated the biomechanical pattern of internal fixation of distal humerus fracture as well as the postoperative safe activity window and elucidated the enhancement path of functional recovery of distal humerus fracture utilizing AnyBody musculoskeletal dynamics analysis. By means of AnyBody musculoskeletal dynamics analysis, the humerus stress migration path showed anatomical-dependent characteristics, with gradient transfer from the hawks' fossa to the distal lateral condyle in flexion. Parallel plates stabilized the IFM in the bone healing window (0.06-0.20 mm) at 0-80° of flexion, whereas vertical plates breached the critical threshold (0.48 mm) in the IFM at > 30° of flexion. This reveals the law of mechanical matching between plate configuration and rehabilitation. There was a clear angle-dependent relationship between flexion angle and inter-fracture gap fragment motion (IFM). The IFM values tended to increase with increasing flexion and extension angles. When using parallel plates, allowing 0-80° of elbow flexion ensures better conditions for fracture healing. When using vertical plates, especially posterior medial plates active elbow flexion should be limited to about 30°.

conclusionsIn this study, we quantified the mechanical effect of muscle contraction force on the stability of internal fixation of distal humerus C-type fracture and revealed the biomechanical law in the postoperative period; we established a simulation model of dynamic and static loading and proposed a 'safe activity window' for postoperative exercise, which confirms the high stiffness of the parallel steel plate and the control of the angle of early active activity (≤ 80° of flexion). Flexion of more than 30° in the case of vertical plates leads to shear micromotion overruns (> 0.48 mm).

Indexed as

Finite Element AnalysisFracture Fixation, InternalHumeral FracturesBiomechanical PhenomenaBone PlatesHumansMaleRange of Motion, ArticularWeight-BearingBiomechanicsDistal humerus fractureElbow motionFinite element analysisFracture healingInternal fixationMusculoskeletal dynamics

Identifiers

PMID40380213
PMCPMC12084957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.