Evidence map›Paper›PMID 40380138›Full record

SynthesisBMC medical informatics and decision making2025

Secondary use of health records for prediction, detection, and treatment planning in the clinical decision support system: a systematic review.

Dipendra Pant, Øystein Nytrø, Bennett L Leventhal, Carolyn Clausen, Kaban Koochakpour, Line Stien, Odd Sverre Westbye, Roman Koposov, Thomas Brox Røst, Thomas Frodl and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dipendra PantDepartment of Computer Science, Norwegian University of Science and Technology, Trondheim, Norway. dipendra.pant@ntnu.no.
Øystein NytrøDepartment of Computer Science, Norwegian University of Science and Technology, Trondheim, Norway.
Bennett L LeventhalThe University of Chicago, Chicago, Illinois, USA.
Carolyn ClausenRegional Centre for Child and Youth Mental Health and Child Welfare (RKBU Central Norway), Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Kaban KoochakpourDepartment of Computer Science, Norwegian University of Science and Technology, Trondheim, Norway.
Line StienRegional Centre for Child and Youth Mental Health and Child Welfare (RKBU Central Norway), Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Odd Sverre WestbyeRegional Centre for Child and Youth Mental Health and Child Welfare (RKBU Central Norway), Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Roman KoposovRegional Centre for Child and Youth Mental Health and Child Welfare (RKBU North), UiT The Arctic University of Norway, Tromsø, Norway.
Thomas Brox RøstDepartment of Computer Science, Norwegian University of Science and Technology, Trondheim, Norway.
Thomas FrodlRWTH University of Aachen, Aachen, Germany.
Norbert SkokauskasRegional Centre for Child and Youth Mental Health and Child Welfare (RKBU Central Norway), Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to understand how secondary use of health records can be done for prediction, detection, treatment recommendations, and related tasks in clinical decision support systems.

methodsArticles mentioning the secondary use of EHRs for clinical utility, specifically in prediction, detection, treatment recommendations, and related tasks in decision support were reviewed. We extracted study details, methods, tools, technologies, utility, and performance.

resultsWe found that secondary uses of EHRs are primarily retrospective, mostly conducted using records from hospital EHRs, EHR data networks, and warehouses. EHRs vary in type and quality, making it critical to ensure their completeness and quality for clinical utility. Widely used methods include machine learning, statistics, simulation, and analytics. Secondary use of health records can be applied in any area of medicine. The selection of data, cohorts, tools, technology, and methods depends on the specific clinical utility.

conclusionThe process for secondary use of health records should include three key steps: 1. Validation of the quality of EHRs, 2. Use of methods, tools, and technologies with proactive training, and 3. Multidimensional assessment of the results and their usefulness.

trial registrationPROSPERO registration number CRD42023409582.

Indexed as

Decision Support Systems, ClinicalElectronic Health RecordsHumansClinical decision supportElectronic health recordSecondary useSystematic review

Identifiers

PMID40380138
PMCPMC12083156

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.