ArticleNeurosurgical review2025
The impact of frailty on functional recovery and discharge dispositions in patients undergoing urgent neurosurgical care.
Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- [Frequent neurosurgically treatable diseases in geriatric patients].Zeitschrift fur Gerontologie und Geriatrie · 2026Article
- Frailty in Parkinson's disease: time to integrate it into treatment decision-making?Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty indices have emerged as robust predictors of morbidity and mortality following neurosurgical interventions. However, their impact on long-term functional and cognitive outcomes remains insufficiently characterised. This study evaluated the prognostic significance of frailty in patients undergoing emergency neurosurgical care and subsequent neurorehabilitation. Based on a cumulative deficit model, a validated 34-item Frailty Index (FI) was applied retrospectively to patients admitted for acute neurosurgical care at a tertiary academic centre and transferred to a specialised neurological rehabilitation facility. Perioperative clinical data, postoperative complications, and discharge dispositions were analysed. A total of 236 patients (median age: 64 years) were included, with 75 (31.8%) classified as "Fit," 87 (36.9%) as "Semi-fit," and 74 (31.4%) as "Frail." Only 13 (17.6%) frail patients returned home post-rehabilitation, compared to 64 (85.3%) fit and 61 (70.1%) semi-fit patients (p = 0.0006). Multivariable logistic regression confirmed FI as an independent predictor of unfavourable discharge destinations (hospital or nursing home vs. home; adjusted odds ratio: 3.615, 95% CI: 1.655-5.580; p = 0.0094). Frailty significantly influences postoperative recovery, predicting greater disability, lower neurological and cognitive function, and unfavourable discharge outcomes. Incorporating frailty assessment into routine emergency practice and research protocols may refine risk stratification and inform clinical decision-making for acutely ill patients undergoing neurosurgical interventions.
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Registered trials
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