Evidence map›Paper›PMID 40379996›Full record

ReviewNature medicine2025

Health impacts of exposure to synthetic chemicals in food.

Jane Muncke, Mathilde Touvier, Leonardo Trasande, Martin Scheringer

Abstract readReview
In one paragraph

Review in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Review
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Bioprotective Strategies to ControlInternational journal of molecular sciences · 2025
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jane MunckeFood Packaging Forum Foundation, Zurich, Switzerland. jane.muncke@fp-forum.org.ORCID http://orcid.org/0000-0002-6942-0594
Mathilde TouvierNutritional Epidemiology Research Team (EREN), Center of Research in Epidemiology and Statistics, CNAM, INRAE, INSERM, Université Sorbonne Paris Nord and Université Paris Cité, Bobigny, France.ORCID http://orcid.org/0000-0002-8322-8857
Leonardo TrasandeDepartment of Pediatrics and Department of Population Health, New York University School of Medicine, New York City, NY, USA.
Martin ScheringerETH Zürich, Zurich, Switzerland.

Funding

The NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5M
The NYU Children’s Health & Environment Study: an ECHO CohortUG3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2016 to 2024
$26.5M
Translation CoreP2CES033423 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHAU TRINH-SHEVRIN, Lorna Thorpe · 2022 to 2026
$5.1M
Developmental Origins of Kidney Function in Early Life and Environmental RisksR01ES032214 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MALAGA-DIEGUEZ, LAURA, TRASANDE, LEONARDO · 2020 to 2024
$3.5M
Preconceptual Bisphenol and Phthalate Effects on Early Embryonic DevelopmentR01ES029779 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2018 to 2023
$2.7M
Agence Nationale de la Recherche (French National Research Agency) 2030 ANR-24-RRII-0005NIEHS NIH HHS P2C ES033423NIEHS NIH HHS R01 ES029779NIEHS NIH HHS R01 ES032214NIH HHS UG3 OD023305NIH HHS UH3 OD023305U.S. Department of Health & Human Services | National Institutes of Health (NIH) P2CES033423U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01ES029779U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01ES032214U.S. Department of Health & Human Services | National Institutes of Health (NIH) UG3OD023305
6 · The paper itself

Abstract

Humans are widely exposed to synthetic chemicals, especially via food. The types of chemical contaminants in food (including food contact chemicals) are diverse, and many of these are known to be hazardous, with mounting evidence that some contribute to noncommunicable diseases. The increasing consumption of ultra-processed foods, which contain synthetic chemicals, also contributes to adverse health. If the chemical contamination of foods were better characterized, then this issue would likely receive more attention as an important opportunity for disease prevention. In this Review, we discuss types and sources of synthetic food contaminants, focusing on food contact chemicals and their presence in ultra-processed foods. We outline future research needs and highlight possible responses at different food system levels. A sustainable transition of the food system must address the health impacts of synthetic chemicals in food; we discuss existing solutions that do justice to the complexity of the issue while avoiding regrettable substitutions and rebound effects.

Indexed as

Food ContaminationHumans

Identifiers

PMID40379996
PMCPMC12442484

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.