Evidence map›Paper›PMID 40379862›Full record

Trial reportWorld journal of urology2025

Prospective randomized study on the efficacy of tamsulosin, solifenacin, and their combination in relieving lower urinary tract symptoms in ureteric stent patients: insights from the brief-form Chinese USSQ.

Peter Hanna, Mohamed A Fahmy, Mohamed M Hussein, Amr Alam El-Din

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter HannaDepartment of Urology, Aswan University, Aswan, Egypt. dr.peter444@gmail.com.ORCID http://orcid.org/0000-0002-4331-3715
Mohamed A FahmyDepartment of Urology, Aswan University, Aswan, Egypt.
Mohamed M HusseinDepartment of Urology, Aswan University, Aswan, Egypt.
Amr Alam El-DinDepartment of Urology, Aswan University, Aswan, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAssess the efficacy of selective alpha-1 blocker (tamsulosin) and antimuscarinic (solifenacin) as well as their combination in alleviating lower urinary tract symptoms in patients with ureteric stents using the brief-form Chinese version of the USSQ.

methodsA prospective randomized control study was conducted from May 2023 to October 2024 in the Urology department at Aswan University Hospital involving 160 consecutive patients undergoing DJ insertion after uncomplicated ureteroscopy. All patients are randomized into 4 groups receiving different treatments. Groups A, B, C, and D received a placebo, tamsulosin 0.4 mg, solifenacin 5 mg, and combinations respectively. IPSS and USSQ (brief-version) were collected and analyzed on the 1st day, 1st week, and 3rd week postoperative.

resultsIn all, 158 patients completed the study, 39 patients for Group A and Group B, while 40 patients for Group C and Group D. Baseline characteristics were comparable among all groups. Group (D) showed a significant decrease in mean ± (SD) IPSS 9.5 (± 1.4), and 7.7 (± 1.3) on 1st week and 3rd week postoperative respectively. Regarding USSQ, group (D) showed significantly lower scores compared to groups (A), (B), and (C) on the 1st day, 1st week, and 3rd week postoperatively (p < 0.001, p < 0.001, p < 0.001; respectively).

conclusionThe brief-form USSQ is a useful, reliable substitute for evaluating stent-related symptoms. Our findings support the notion that tamsulosin/solifenacin combinations have considerably reduced LUTS linked to the placement of ureteral stents.

Indexed as

Adrenergic alpha-1 Receptor AntagonistsLower Urinary Tract SymptomsMuscarinic AntagonistsPostoperative ComplicationsSolifenacin SuccinateStentsTamsulosinAdultAgedChinaDrug Therapy, CombinationFemaleHumansMaleMiddle AgedProspective StudiesAdrenergic alpha-1 Receptor AntagonistsMuscarinic AntagonistsSolifenacin SuccinateTamsulosinUrological AgentsSolifenacinTamsulosinUpper ureter symptoms scoreUreteral stent

Identifiers

PMID40379862
PMCPMC12084230

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.