Evidence map›Paper›PMID 40379808›Full record

ArticleEvidence-based dentistry2025

Can plaque-identifying toothpastes inspire better oral hygiene among orthodontic patients?

Neeraj Gugnani, Shalini Gugnani

Abstract read
PubMed Publisher
In one paragraph

Article in Evidence-based dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Neeraj GugnaniDepartment of Pedodontics and Preventive Dentistry, DAV (C) Dental College Yamunanagar, Haryana, India. drgugnani@gmail.com.
Shalini GugnaniDepartment of Periodontics and Oral Implantology, DAV (C) Dental College Yamunanagar, Haryana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

a commentary onVan Doornik SP, van Kammen L, Ren Y, Manton D J, Kuijpers-Jagtman A M. Effect of a plaque-identifying toothpaste on plaque amount in 12-16-year-olds with fixed orthodontic appliances: a randomised, double-blind, controlled clinical trial. Orthod Craniofac Res 2025; https://doi.org/10.1111/ocr.12904 .

designThe study aimed to evaluate the effectiveness of a plaque-identifying toothpaste in improving plaque removal among adolescents undergoing fixed orthodontic treatment. This was a double-blind, parallel-group RCT with active-control, having two groups with equal allocation ratio. CASE SELECTION: Participants were healthy adolescents aged 12-16 years with fixed orthodontic appliances in both arches for a minimum of three months. Another inclusion criterion was presence of permanent teeth (canine to canine), while exclusion criteria included toothpaste allergies, syndromic conditions, craniofacial abnormalities, and participants from the same household. A total of 77 participants were included, and were randomized into the intervention (plaque-identifying toothpaste) and control groups (conventional toothpaste). DATA ANALYSIS: The intervention group was provided with a toothpaste containing disclosing dyes (Mara Expert) intended for plaque-identification, while the control group was provided with a standard toothpaste (Colgate Fresh Gel). The patients were instructed to use the toothpastes for a period of 4-7 weeks, following which assessments were done. The primary outcome included evaluation of changes in the plaque accumulation from baseline to follow-up, as assessed by determining change in fluorescence, which was evaluated using Quantitative Light-Induced Fluorescence (QLF). Secondary outcomes were assessed through a structured questionnaire focusing on user experience and self-perceived oral hygiene behaviours.

resultsPatients in both groups showed plaque reduction over time. But the difference observed in plaque reduction between the two groups was not found to be statistically significant (F = 0.211; p = 0.647). However, in the questionnaire, users of the plaque-disclosing toothpaste felt 'they are removing more plaque with their new toothpaste' (p = 0.018), and some participants found its colour to be unappealing (p = 0.028). Overall compliance was good, and no adverse effects were reported.

conclusionsPlaque-identifying toothpaste did not demonstrate a superior clinical reduction in plaque levels compared to the control, though increased awareness of plaque removal was observed in the intervention group.

Indexed as

Dental PlaqueOral HygieneOrthodontic Appliances, FixedToothpastesAdolescentChildDouble-Blind MethodFemaleHumansMaleRandomized Controlled Trials as TopicToothpastes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.