ArticleEvidence-based dentistry2025
Can plaque-identifying toothpastes inspire better oral hygiene among orthodontic patients?
Article in Evidence-based dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
a commentary onVan Doornik SP, van Kammen L, Ren Y, Manton D J, Kuijpers-Jagtman A M. Effect of a plaque-identifying toothpaste on plaque amount in 12-16-year-olds with fixed orthodontic appliances: a randomised, double-blind, controlled clinical trial. Orthod Craniofac Res 2025; https://doi.org/10.1111/ocr.12904 .
designThe study aimed to evaluate the effectiveness of a plaque-identifying toothpaste in improving plaque removal among adolescents undergoing fixed orthodontic treatment. This was a double-blind, parallel-group RCT with active-control, having two groups with equal allocation ratio. CASE SELECTION: Participants were healthy adolescents aged 12-16 years with fixed orthodontic appliances in both arches for a minimum of three months. Another inclusion criterion was presence of permanent teeth (canine to canine), while exclusion criteria included toothpaste allergies, syndromic conditions, craniofacial abnormalities, and participants from the same household. A total of 77 participants were included, and were randomized into the intervention (plaque-identifying toothpaste) and control groups (conventional toothpaste). DATA ANALYSIS: The intervention group was provided with a toothpaste containing disclosing dyes (Mara Expert) intended for plaque-identification, while the control group was provided with a standard toothpaste (Colgate Fresh Gel). The patients were instructed to use the toothpastes for a period of 4-7 weeks, following which assessments were done. The primary outcome included evaluation of changes in the plaque accumulation from baseline to follow-up, as assessed by determining change in fluorescence, which was evaluated using Quantitative Light-Induced Fluorescence (QLF). Secondary outcomes were assessed through a structured questionnaire focusing on user experience and self-perceived oral hygiene behaviours.
resultsPatients in both groups showed plaque reduction over time. But the difference observed in plaque reduction between the two groups was not found to be statistically significant (F = 0.211; p = 0.647). However, in the questionnaire, users of the plaque-disclosing toothpaste felt 'they are removing more plaque with their new toothpaste' (p = 0.018), and some participants found its colour to be unappealing (p = 0.028). Overall compliance was good, and no adverse effects were reported.
conclusionsPlaque-identifying toothpaste did not demonstrate a superior clinical reduction in plaque levels compared to the control, though increased awareness of plaque removal was observed in the intervention group.
Indexed as
Identifiers
40379808What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.