FullBlock-Assisted Percutaneous Carotid Artery Revascularization: A Novel Approach for Enhanced Neuroprotection.

Bo Yu, Kristine J S Kwan, Jiong Zhou, Jin-Dong Tong, Shuai Jiang, Jin-Yun Tan, Wei-Hao Shi, Jing-Dong Tang

Abstract readCase Reports

In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bo YuDepartment of Vascular Surgery, Fudan University Pudong Medical Center, Shanghai, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China; Vascular Surgery Division, General Surgery Department, Huashan Hospital Affiliated to Fudan University, Shanghai, China. Electronic address: YBxg0306@163.com.

Kristine J S KwanDepartment of Vascular Surgery, Fudan University Pudong Medical Center, Shanghai, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China.

Jiong ZhouDepartment of Vascular Surgery, Fudan University Pudong Medical Center, Shanghai, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China.

Jin-Dong TongDepartment of Vascular Surgery, Fudan University Pudong Medical Center, Shanghai, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China.

Shuai JiangDepartment of Vascular Surgery, Fudan University Pudong Medical Center, Shanghai, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China.

Jin-Yun TanShanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China; Vascular Surgery Division, General Surgery Department, Huashan Hospital Affiliated to Fudan University, Shanghai, China.

Wei-Hao ShiShanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China; Vascular Surgery Division, General Surgery Department, Huashan Hospital Affiliated to Fudan University, Shanghai, China.

Jing-Dong TangDepartment of Vascular Surgery, Fudan University Pudong Medical Center, Shanghai, China; Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report describes a first-in-human case of percutaneous carotid artery revascularization (PCAR) using FullBlock, a neuroprotective system that consists of a dual-occlusion balloon and reverse-flow neuroprotective system. The patient was a 77-year-old woman with severe left internal carotid artery stenosis and multiple cardiovascular comorbidities. She was deemed unsuitable for carotid endarterectomy. PCAR with stenting was performed successfully with general anesthesia. Neuroprotection depended on controllable reverse hemodynamics established with the femoral vein and communicating intracranial arteries. Atherosclerotic plaques were filtered in the extra-anatomic reverse flow tube. One-month follow-up was favorable. This case demonstrates the feasibility of FullBlock-assisted PCAR with stenting as a promising alternative for high-risk patients. Transradial and femoral access can be avoided, adding potential benefits of reduced operative complexity and enhanced neuroprotection.

Indexed as

carotid artery stenosiscarotid endarterectomytranscarotid artery revascularizationtransfemoral carotid artery stenting

Identifiers

PMID40379372

DOI10.1016/j.jaccas.2025.103629

PMCPMC12144978

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.