Evidence map›Paper›PMID 40379318›Full record

ArticleBMJ open2025

Patient experiences and expectations of faecal immunochemical testing for investigation of colorectal cancer symptoms: a cross-sectional qualitative interview study with patients and practitioners in the UK.

Adam Biran, Christina Dobson, Colin J Rees, Willie Hamilton, David Humes, Laura Jane Neilson, James Turvill, Christian von Wagner, John Whelpton, Linda Sharp

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Sociodemographic variation in symptomatic faecal immunochemical testing return: a population-based analysis of 125 659 patients.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adam Biran *Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK adam.biran@newcastle.ac.uk.ORCID http://orcid.org/0009-0002-0702-2109
Christina Dobson *Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Colin J ReesPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Willie HamiltonUniversity of Exeter Medical School, Exeter, UK.
David HumesGastrointestinal and Liver Theme, NIHR Nottingham Biomedical Research Centre, Nottingham, UK.
Laura Jane NeilsonPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
James TurvillYork and Scarborough Teaching Hospitals NHS Foundation Trust, York, UK.ORCID http://orcid.org/0000-0003-3068-5015
Christian von WagnerDepartment of Epidemiology and Public Health, University College London, London, UK.ORCID http://orcid.org/0000-0002-7971-0691
John WhelptonLay Investigator, Newcastle University, Newcastle upon Tyne, UK.
Linda SharpPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0001-9515-1722

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFaecal immunochemical testing (FIT) is now commonplace in the UK to prioritise symptomatic patients for urgent gastrointestinal investigation. The test requires a stool sample to be collected at home by the patient and returned for analysis. In this qualitative study, we sought to understand the feasibility and acceptability of FIT-based triage for patients.

designA cross-sectional, qualitative, experiential interview study.

settingRecruitment was through three participating UK NHS sites (Yorkshire, Midlands, North-East). Health professionals were also identified through membership of the BSG/ACPGBI Symptomatic FIT Guideline Development Group and snowball sampling.

participantsWe interviewed 21 patients who had completed FIT and been referred for colonoscopy and 30 primary and secondary care health professionals involved in symptomatic FIT delivery.

resultsCompletion of FIT was unproblematic from the perspective of patients who returned the test. However, health professionals expressed concern over non-return. Among patients, understanding of the purpose of FIT and the meaning of results varied. Health professionals acknowledged that ensuring patient understanding of these can be challenging. Patients believed colonoscopy was less likely to miss cancer than FIT. Patients with a family or personal history of cancer were particularly anxious and wanted the reassurance of colonoscopy, even with a negative FIT result.

conclusionsWe found no major barriers to the use of FIT in prioritising symptomatic patients for urgent investigation. Improving communication might increase compliance and, possibly, acceptability of non-referral for colonoscopy in the case of a negative test result.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerFecesOccult BloodAdultAgedAttitude of Health PersonnelColonoscopyCross-Sectional StudiesFemaleHumansInterviews as TopicMaleMiddle AgedPatient Acceptance of Health CareQualitative ResearchAdult gastroenterologyAdult oncologyEndoscopyPrimary Health CareQUALITATIVE RESEARCH

Identifiers

PMID40379318
PMCPMC12086939

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.