Observational studyJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2025
Visual and refractive outcomes up to 5 years of age of dome-shaped macula detected by handheld spectral domain optical coherence tomography in preterm infants.
Observational study in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
purposeTo evaluate long-term visual and refractive outcomes in preterm infants found to have dome-shaped macula on imaging with handheld spectral domain optical coherence tomography (SD-OCT).
methodsThis was a prospective, observational study of preterm infants. Awake handheld SD-OCT was performed at the time of each routine retinopathy of prematurity examination. All visual and refractive (cycloplegic refraction by streak retinoscopy) outcomes were assessed by a single, masked, fellowship-trained pediatric ophthalmologist at 9 months, 2 years, and 5 years of age.
resultsOf 95 included preterm infants (52% male; mean birth weight, 1006.14 ± 292.96 g; mean gestational age, 28.38 ± 2.87 weeks), 58 (61%) had dome-shaped macula in at least one eye with good kappa agreement (0.71 ± 0.04; 95% Cl, 0.63-0.80). No differences in spherical equivalent were seen at 9 months (+1.80 ± 1.67 vs +1.55 ± 1.89 [P = 0.39]), 2 years (+1.34 ± 1.89 vs +1.03 ± 1.20 [P = 0.60]), or 5 years of age (+0.51 ± 1.51 vs +0.72 ± 1.66 [P = 0.12]). There were also no differences in logMAR visual acuity at 9 months (P = 0.41), 2 years (P = 0.62), or 5 years (P = 0.60) of age. Rates of astigmatism or strabismus did not differ at any time point (P > 0.10).
conclusionsDome-shaped macula detected by handheld SD-OCT in infancy was not associated with differences in visual acuity, refractive error, or strabismus at 9 months, 2 years, or 5 years of age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.