ArticlePloS one2025
Seroprevalence of hepatitis A virus infection in urban and rural areas in Vietnam.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Evolving trends in hepatitis A epidemiology: Shifting patterns, emerging risks, and future strategies.World journal of virology · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesThe prevalence of hepatitis A virus (HAV) is associated with socioeconomic conditions, access to clean drinking water, and improvements in sanitation. In Vietnam, epidemiological data on HAV have been limited over the past two decades. This study aims to assess age-specific HAV seroprevalence across two distinct geographic regions, urban and rural areas, and identify the risk factors associated with HAV seropositivity in Vietnam.
methodsThis cross-sectional seroprevalence study was conducted in two distinct areas in Vietnam. Serological testing for anti-HAV total antibodies was performed, and socio-demographic questionnaires were administered to all participants. The age at the midpoint of population immunity (AMPI) was calculated and analyzed.
resultsA total of 1,281 participants aged 1-80 years were included, with 649 from urban areas and 632 from rural areas. Of the total participants, 33.2% were aged <15 years. Overall, HAV seropositivity was 69.2%, with urban areas exhibiting significantly lower seropositivity (57.9%) compared to rural areas (80.7%) (p < 0.001). The AMPI was 29 years, indicating Vietnam is at intermediate HAV endemicity. Multivariate analysis identified key risk factors for HAV infection, including age and rural residence. Conversely, participants with higher educational levels and those who consumed boiled drinking water were less likely to be HAV seropositive.
conclusionsThe study identified significant differences in the HAV seroprevalence between urban and rural areas, providing critical data for public health officials. These findings highlight the key role of targeted public health interventions and vaccination programs in mitigating HAV infection rates and reducing the disease burden, particularly among high-risk populations in Vietnam.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.