Evidence map›Paper›PMID 40378216›Full record

ArticleScience advances2025

Dynamics of bacterial operons during genome-wide stresses is influenced by premature terminations and internal promoters.

Rahul Jagadeesan, Suchintak Dash, Cristina S D Palma, Ines S C Baptista, Vatsala Chauhan, Jarno Mäkelä, Andre S Ribeiro

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Thermal Shifts Dominate Single-Gene Responses to Transcription-Targeting Antibiotics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  6. ESX-5 Deletions inbioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rahul JagadeesanFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0001-9537-4221
Suchintak DashFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0003-2108-5448
Cristina S D PalmaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0002-0390-1440
Ines S C BaptistaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0001-7041-4135
Vatsala ChauhanFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jarno MäkeläInstitute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
Andre S RibeiroFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0002-7255-5211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial gene networks have operons, each coordinating several genes under a primary promoter. Half of the operons in

Indexed as

Genome, BacterialOperonPromoter Regions, GeneticStress, PhysiologicalBacillus subtilisDNA-Directed RNA PolymerasesEscherichia coliGene Expression Regulation, BacterialHelicobacter pyloriDNA-Directed RNA Polymerases

Identifiers

PMID40378216
PMCPMC12083536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.