Evidence map›Paper›PMID 40378006›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

The benefits and dangers of anthropomorphic conversational agents.

Sandra Peter, Kai Riemer, Jevin D West

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Ethical Considerations in Personal Health Large Language Models.Journal of medical Internet research · 2026
    Article
  5. Review
  6. Article
  7. TechnologicalNature. Mental health · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sandra Peter *University of Sydney Business School, The University of Sydney, Sydney, NSW 2006, Australia.
Kai Riemer *University of Sydney Business School, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-2348-8315
Jevin D West *Center for an Informed Public, Information School, University of Washington, Seattle, WA 98195.ORCID 0000-0002-4118-0322

Funding

John S. and James L. Knight Foundation (KF) UWCIPNational Science Foundation (NSF) 2120496
6 · The paper itself

Abstract

A growing body of research suggests that the recent generation of large language model (LLMs) excel, and in many cases outpace humans, at writing persuasively and empathetically, at inferring user traits from text, and at mimicking human-like conversation believably and effectively-without possessing any true empathy or social understanding. We refer to these systems as "anthropomorphic conversational agents" to aptly conceptualize the ability of LLM-based systems to mimic human communication so convincingly that they become increasingly indistinguishable from human interlocutors. This ability challenges the many efforts that caution against "anthropomorphizing" LLMs, attaching human-like qualities to nonhuman entities. When the systems themselves exhibit human-like qualities, calls to resist anthropomorphism will increasingly fall flat. While the AI industry directs much effort into improving the reasoning abilities of LLMs-with mixed results-the progress in communicative abilities remains underappreciated. In this perspective, we aim to raise awareness for both the benefits and dangers of anthropomorphic agents. We ask: should we lean into the human-like abilities, or should we aim to dehumanize LLM-based systems, given concerns over anthropomorphic seduction? When users cannot tell the difference between human interlocutors and AI systems, threats emerge of deception, manipulation, and disinformation at scale. We suggest that we must engage with anthropomorphic agents across design and development, deployment and use, and regulation and policy-making. We outline in detail implications and associated research questions.

Indexed as

Artificial IntelligenceCommunicationLanguageHumansanthropomorphic agentsanthropomorphic conversational agentsgenerative AIlarge language models

Identifiers

PMID40378006
PMCPMC12146756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.