Evidence map›Paper›PMID 40377894›Full record

ArticleMolecular neurobiology2025

Ontogenic, Immunological, and Behavioral Changes of Crack Cocaine Exposure During the Gestational Period.

Yngrid Mickaelli Oliveira Dos Santos, Igor Santana-Melo, Amanda Larissa Dias Pacheco, Milenna Maria Jatoba Hasten Reiter, Maisa de Araújo Costa, Keyla Silva Nobre Pires, Fernanda Maria Araújo de Souza, Jucilene Freitas-Santos, Mayara Rodrigues Barbosa, Jeferson Santana Ursulino and 12 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Yngrid Mickaelli Oliveira Dos Santos *Institute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0003-4590-1665
Igor Santana-Melo *Institute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil. igor_melo777@hotmail.com.ORCID http://orcid.org/0000-0001-8758-3613
Amanda Larissa Dias PachecoInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0002-6533-4058
Milenna Maria Jatoba Hasten ReiterInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0009-0004-0751-8862
Maisa de Araújo CostaInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0001-7557-4357
Keyla Silva Nobre PiresInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0001-7426-5675
Fernanda Maria Araújo de SouzaInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0002-9514-3092
Jucilene Freitas-SantosInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0001-8302-200X
Mayara Rodrigues BarbosaInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0003-3625-5139
Jeferson Santana UrsulinoInstitute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Maceio, AL, Brazil.ORCID http://orcid.org/0000-0002-6292-4546
Marvin Paulo LinsInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0003-4247-0345
Rayssa Gabriely Duarte TorresInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0001-7276-1368
Amanda de Barros CoutinhoInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0009-0001-1314-309X
Eloisa Bortolote OliosiInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0009-0009-2605-9338
Bianca Rodrigues Melo da SilvaInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0002-7666-364X
Keylla Lavínia da Silva OliveiraInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0001-9790-5364
Daniel Leite Goes GitaiInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0001-7056-2373
Ana Catarina Rezende LeiteInstitute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Maceio, AL, Brazil.ORCID http://orcid.org/0000-0002-3426-3357
Thiago Mendonça de AquinoInstitute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Maceio, AL, Brazil.ORCID http://orcid.org/0000-0001-9138-8466
Marcelo DuzzioniInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0002-2212-8027
Alexandre Urban BorbelyInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil.ORCID http://orcid.org/0000-0001-6737-0901
Olagide Wagner de CastroInstitute of Biological Sciences and Health, Federal University of Alagoas (UFAL), Maceió, Brazil. olagidewww@gmail.com.ORCID http://orcid.org/0000-0002-1874-509X

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 406727/2021-0
6 · The paper itself

Abstract

Crack cocaine has a high addictive power that stimulates the central nervous system (CNS), and its high consumption by women of reproductive age has generated many challenges for public health. Crack cocaine use by pregnant women has been correlated with CNS malformations, cell damage, and changes in the immune system. Our purpose was to evaluate the effects of gestational exposure to crack cocaine in pregnant rats on ectoplacental cone cells, immune organs, maternal behavior, anxiety-like phenotype, metabolites, and sensorimotor reflex development of offspring. Pregnant rats were exposed to air or crack cocaine (200 mg) from the 5th gestational day (5

Indexed as

Behavior, AnimalCrack CocainePrenatal Exposure Delayed EffectsAnimalsAnxietyFemaleLactationMaternal BehaviorPregnancyRatsRats, WistarCrack CocaineLymphoid organMetabolomicsPlacenta. Maternal-infant bondingSubstance of abuse

Identifiers

PMID40377894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.