Evidence map›Paper›PMID 40377823›Full record

ArticleAging clinical and experimental research2025

Longitudinal effects of diet quality on healthy aging - Focus on cardiometabolic health: findings from the Canadian longitudinal study on aging (CLSA).

Farhad Vahid, Piotr Wilk, Torsten Bohn

Abstract read
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In one paragraph

Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Associations and interaction effects of socioeconomic, lifestyle, and genetic factors on intrinsic capacity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Farhad VahidNutrition and Health Research Group, Department of Precision Health, Luxembourg Institute of Health, 1A, B Edison, Strassen, L-1445, Luxembourg.ORCID http://orcid.org/0000-0002-7380-3790
Piotr WilkDepartment of Epidemiology and Biostatistics, Western University, London, ON, Canada.ORCID http://orcid.org/0000-0001-7217-4163
Torsten BohnNutrition and Health Research Group, Department of Precision Health, Luxembourg Institute of Health, 1A, B Edison, Strassen, L-1445, Luxembourg. Torsten.bohn@lih.lu.ORCID http://orcid.org/0000-0002-7825-0697

Funding

Fonds National de la Recherche Luxembourg INTER/Mobility/18029743
6 · The paper itself

Abstract

backgroundHypertension, a major concern for older adults, contributes to morbidity and mortality by increasing the risk of cardiovascular disease, stroke, kidney dysfunction, and cognitive decline. A healthy diet plays a vital role in limiting chronic disease progression in aging populations.

aimThis study investigated the association between diet quality and healthy aging, focusing on blood pressure measurements (BPMs), using the Canadian Longitudinal Study on Aging (CLSA).

methodsParticipants aged 45-85 years at baseline were followed for up to nine years. Mediterranean diet score (MDS) was determined based on the validated short diet questionnaire (SDQ). BP and mean arterial pressure (MAP) were measured at baseline (2010), follow-up 1 (2015), and follow-up 2 (2018). Linear regression models (LRMs), linear mixed-effects models (LMMs), and latent change score models (LCSMs) examined the associations and longitudinal effect between MDS and BPMs, adjusted for potential confounders. Individuals who participated in all three waves (n = 25,377) were included.

resultsFully adjusted LRMs showed significant (p < 0.001) inverse associations between MDS and all BPMs across all time points, e.g., 1 unit increase in the MDS (min0-max50) was associated with a 0.058 mmHg decrease of diastolic BP (DBP) (β=-0.058), 0.052 mmHg systolic BP (SBP) (β=-0.052), and 0.056 mmHg MAP (β=-0.056). LCSMs indicated that a 1-unit higher baseline MDS was significantly associated with 0.090 mmHg reductions in DBP at follow-up 2 (β=-0.090,p < 0.001), 0.078 mmHg for SBP (β=-0.078,p = 0.002) and 0.076 mmHg for MAP (β=-0.076,p = 0.003). Changes in MDS during follow-ups showed no consistent significant associations with BPMs at follow-up 1 or 2. DISCUSSION AND

conclusionHigher MDS was associated with lower BPMs over time. This study highlights the role of diet quality in healthy aging and mitigating cardiometabolic risk in older adults.

Indexed as

AgingDiet, HealthyDiet, MediterraneanHealthy AgingAgedAged, 80 and overBlood PressureCanadaCardiovascular DiseasesFemaleHumansHypertensionLongitudinal StudiesMaleMiddle AgedChronic diseaseCLSADietary indicesDietary patternsHypertension prevention & controlNutritional biomarkersVessel health

Identifiers

PMID40377823
PMCPMC12084232

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.