Evidence map›Paper›PMID 40377812›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2025

Nutritional Characterization and Metabolic Profiling of Bioactive Compounds in Cajanus scarabaeoides Seeds Using GC-MS and LC-MS Analysis.

Rajesh Rokkam, Felicity Pinipay, John Titus Killo, Satyanarayana Botcha, Raghava Rao Tamanam

Abstract read
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In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rajesh RokkamDepartment of Biochemistry, College of Science and Technology, Andhra University, South Campus, Visakhapatnam, Andhra Pradesh, 530003, India. rrajesh125@gmail.com.
Felicity PinipayDepartment of Biochemistry, College of Science and Technology, Andhra University, South Campus, Visakhapatnam, Andhra Pradesh, 530003, India.
John Titus KilloDepartment of Biochemistry, College of Science and Technology, Andhra University, South Campus, Visakhapatnam, Andhra Pradesh, 530003, India.
Satyanarayana BotchaDepartment of Biochemistry, College of Science and Technology, Andhra University, South Campus, Visakhapatnam, Andhra Pradesh, 530003, India.
Raghava Rao TamanamDepartment of Biochemistry, College of Science and Technology, Andhra University, South Campus, Visakhapatnam, Andhra Pradesh, 530003, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cajanus scarabaeoides, a wild relative of Cajanus cajan, is renowned for its medicinal properties and rich bioactive compounds, particularly within its seeds, which are valuable for their storage of primary and secondary metabolites with potential pharmacological applications. This study aimed to comprehensively analyze physical properties, nutritional content, and the metabolic profile of Cajanus scarabaeoides seeds to understand their medicinal potential. Physical characteristics such as seed weight, volume, density, hydration capacity, and swelling index were measured, alongside a detailed nutritional assessment that quantified moisture, ash, crude fat, fiber, protein, carbohydrate, and vitamin content (A, C, E), as well as essential minerals. Metabolic profiling was conducted using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS), identifying 117 non-volatile and 135 volatile metabolites. The chloroform extract showed the highest concentration of volatile metabolites (55), while the chloroform and ethyl acetate extracts were rich in non-volatile compounds (45 and 43, respectively), including flavonoids, polyphenols, and organic acids, which are associated with antioxidant and anti-inflammatory properties. Multivariate analysis, using supervised partial least squares discriminant analysis (PLS-DA), identified differential metabolites, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed the involvement of metabolic pathways such as unsaturated fatty acid biosynthesis, metabolism of xenobiotics by cytochrome P450, and Drug metabolism - other enzymes. The rich composition of bioactive metabolites, especially flavonoids and polyphenols, underscores the medicinal value of Cajanus scarabaeoides seeds, suggesting significant potential for developing antioxidant and anti-inflammatory treatments.

Indexed as

CajanusPhytochemicalsPlant ExtractsSeedsAntioxidantsChromatography, LiquidFlavonoidsGas Chromatography-Mass SpectrometryLiquid Chromatography-Mass SpectrometryMass SpectrometryMetabolomeMetabolomicsNutritive ValuePolyphenolsAntioxidantsFlavonoidsPhytochemicalsPlant ExtractsPolyphenolsBioactive compoundsCajanus scarabaeoidesLegume seedsMass spectrometryMetabolites

Identifiers

PMID40377812

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.