Evidence map›Paper›PMID 40377768›Full record

ArticleMaternal and child health journal2025

Content Analysis of Maternal Toxicology Testing Policies to Inform Equity in Substance Use Disorder Identification.

Leah L Habersham, Sugy Choi, Michelle Gelband, Wendy Wilcox, Angela Bianco, Peter S Bernstein, Kima J Taylor, Nihal E Mohamed

Abstract read
In one paragraph

Article in Maternal and child health journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leah L HabershamDepartment of Psychiatry, Department of Obstetrics, Gynecology, & Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Leah.Habersham@mountsinai.org.ORCID http://orcid.org/0000-0002-1561-5265
Sugy ChoiNYU Langone Health, NYU Grossman School of Medicine, New York, NY, USA.
Michelle GelbandDepartment of Psychiatry, Department of Obstetrics, Gynecology, & Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Wendy WilcoxNew York City Health and Hospitals, New York, NY, USA.
Angela BiancoDepartment of Psychiatry, Department of Obstetrics, Gynecology, & Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Peter S BernsteinDepartment of Psychiatry, Department of Obstetrics, Gynecology, & Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kima J TaylorAnka Consulting LLC, McAllen, USA.
Nihal E MohamedDepartment of Psychiatry, Department of Obstetrics, Gynecology, & Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Funding

Advancing Clinical Research Training within Addiction Residency ProgramsR25DA033211 · NIDA · BOSTON MEDICAL CENTER · PI Patrick O'Connor, JEFFREY H. SAMET · 2012 to 2026
$4.2M
Mount Sinai Clinician Scientist Training Program in Emergency Care ResearchT32HL160513 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Lynne D. Richardson · 2022 to 2026
$2.2M
Addiction Institute of Mount Sinai Internal FundsIntramural Research Program, National Institute on Drug Abuse R25DA033211NHLBI Division of Intramural Research T32HL160513NHLBI NIH HHS T32 HL160513NIDA NIH HHS R25 DA033211
6 · The paper itself

Abstract

objectiveAnalyze existing hospital-level policies in New York City (NYC) regarding substance use and substance use disorders (SUDs) during the perinatal period to provide a comprehensive guide for hospital-level policy development, ensuring equitable maternal screening for substance use and SUDs.

methodsMaternal toxicology policies were collected from eight NYC health systems between 1/1/2021 and 12/31/2022. One policy focused exclusively on neonate toxicology testing and thus was excluded. The remaining seven policies were de-identified and underwent a qualitative thematic content analysis using the Health Equity Impact Assessment framework. Two researchers conducted the thematic analysis, and two others reviewed identified themes for distinctions between policies.

resultsSeven hospital-level policies identified four distinct policy approaches (Types A, B, C, and D). The policies varied in their approach to prenatal substance use and SUD identification, highlighting gaps in knowledge and lack of standard guidelines. The different approaches involved combinations of standardized screening tools, toxicology tests, social service referrals, and patient consent procedures, among others. Researchers found that some policies may inadvertently reinforce stigma and bias due to a focus on high-risk characteristics not necessarily indicative of substance use or SUDs.

conclusionMultidisciplinary-informed evidence-based guidelines are needed to address substance use and SUDs during pregnancy. Our findings support the integration of evidence-based screening, brief intervention, and referral to treatment (SBIRT) into policies, and discourage sole reliance on toxicology tests for SUD identification. The study's findings can potentially guide the development of equitable and clinically useful maternal substance use and SUD policies, thereby improving dyad outcomes.

Indexed as

Health EquityHealth PolicySubstance Abuse DetectionSubstance-Related DisordersFemaleHumansNew York CityPregnancyQualitative ResearchChild welfare reportingHealth equityHospital policy analysisInformed consentMaternal toxicology testingNew York City health systemsPerinatal substance use disordersRacial disparities in maternal careSBIRT

Identifiers

PMID40377768
PMCPMC13270262

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.