Evidence map›Paper›PMID 40377424›Full record

ArticleNanomedicine (London, England)2025

Diethyldithiocarbamate-Cu

Marwa M Abu-Serie, María A Blasco

Abstract read
In one paragraph

Article in Nanomedicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Copper, cuproptosis, and cancer: biology concepts of a novel cell death.Apoptosis : an international journal on programmed cell death · 2026
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marwa M Abu-SerieMedical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, (GEBRI), City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, Egypt.
María A BlascoTelomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTargeting cancer stem cells (CSCs)-mediated aggressive features of non-small cell lung cancer (NSCLC) is a promising anticancer approach. This can be accomplished via suppressing critical mediators, such as functional mitochondria, aldehyde dehydrogenase (ALDH)1A, and telomere protectors (telomerase reverse transcriptase (TERT) and telomere repeat binding factor (TRF)1). MATERIALS &

methodsCopper nanocomplexes (diethyldithiocarbamate (DE)-Cu

resultsDE-Cu

conclusionDE-Cu

Indexed as

Carcinoma, Non-Small-Cell LungCopperDitiocarbLung NeoplasmsMetal NanoparticlesMitochondriaTelomeraseAnimalsAntineoplastic AgentsCell Line, TumorCell ProliferationHumansMembrane Potential, MitochondrialMiceMice, NudeNanoparticlesAntineoplastic AgentsCopperDitiocarbTelomerasealdehyde dehydrogenase 1ACancer stem cellsdiethyldithiocarbamate-Cu4O3 nanoparticlesmitochondrial impairment-dependent cuproptosisnon-small cell lung cancertelomerase reverse transcriptase regulatorstelomere protectors

Identifiers

PMID40377424
PMCPMC12140473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.