Evidence map›Paper›PMID 40377277›Full record

ArticleJournal of advanced nursing2026

Mediating Effects of Family and Clinical Characteristics on the Quality of Life of Children With Spina Bifida and Their Parents.

Seung Hyeon Yang, Hyeseon Yun, Hooyun Lee, Kyua Kim, Chang Gi Park, Eun Kyoung Choi

Abstract read
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Article in Journal of advanced nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Seung Hyeon YangCollege of Nursing, Research Institute of AI and Nursing Science, Gachon University, Incheon, Republic of Korea.ORCID https://orcid.org/0000-0003-0824-5961
Hyeseon YunCollege of Nursing and Brain Korea 21 FOUR Project, Yonsei University, Seoul, Republic of Korea.
Hooyun LeeCollege of Nursing and Brain Korea 21 FOUR Project, Yonsei University, Seoul, Republic of Korea.
Kyua KimCollege of Nursing and Brain Korea 21 FOUR Project, Yonsei University, Seoul, Republic of Korea.
Chang Gi ParkCollege of Nursing, University of Illinois Chicago, Chicago, Illinois, USA.
Eun Kyoung ChoiCollege of Nursing and Mo-Im Kim Nursing Research Institute, Yonsei University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-4622-2437

Funding

National Research Foundation of Korea 2022R1A2C1008573
6 · The paper itself

Abstract

aims(1) To determine the mediating effects of children's transition readiness, which reflects self-management skill acquisition, and family resilience on the relationship between parenting stress and the quality of life (QOL) of parents and children with spina bifida (SB). (2) To conduct an exploratory analysis of the differences in the mediating pathways based on the presence of SB-related clinical characteristics.

designA cross-sectional study.

methodsData were collected from a single centre in South Korea between October 2022 and July 2024. Participants included children aged 7-13 years diagnosed with myelomeningocele, lipomyelomeningocele or tethered cord syndrome, along with their parents. Statistical analysis was conducted using SPSS and the MEDYAD macro for actor-partner interdependence mediation model analysis.

resultsFamily resilience significantly mediated the relationship between parenting stress and both child and parent QOL. However, transition readiness was not a significant mediator in the overall sample. Among children with SB-related clinical characteristics, transition readiness significantly mediated the association between parenting stress and child QOL. In contrast, family resilience mediated the relationship between parenting stress and parent QOL. No significant mediators were found in children without SB-related clinical characteristics.

conclusionThis study highlights the mediating role of family resilience and transition readiness in improving the QOL of children with SB, particularly those with clinical characteristics. The findings suggest that interventions should be tailored to address both family resilience and transition readiness, especially for children with SB-related clinical challenges. IMPACT: These findings are valuable for nurses supporting children with SB, as the results highlight the importance of transition education tailored to SB-related clinical characteristics. In particular, nurse-led transition education may play a key role in enhancing transition readiness and improving the QOL of children with SB who have clinical characteristics. PATIENT CONTRIBUTION: None. REPORTING

methodSTROBE Checklist for cross-sectional studies.

Indexed as

ParentingParentsQuality of LifeSpinal DysraphismAdolescentAdultChildCross-Sectional StudiesFemaleHumansMaleRepublic of KoreaResilience, PsychologicalStress, Psychologicalactor‐partner interdependence mediation modelfamily resiliencequality of lifespinal dysraphismtransition

Identifiers

PMID40377277
PMCPMC12907617

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.