ArticleAnnals of medicine2025
Clinical and laboratory indicators predicting coagulase-negative staphylococci as a cause of bloodstream infection among children below five years of age admitted at a tertiary hospital in Dar es Salaam, Tanzania.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Global distribution, antimicrobial resistance, and virulence factors of Staphylococcus epidermidis revealed through population genomics.BMC genomics · 2026Article
- Septic pulmonary embolism in Somali children: a retrospective study from a tertiary hospital.Frontiers in pediatrics · 2026Article
- Regarding clinical and laboratory indicators predicting coagulase-negative staphylococci as a cause of bloodstream infection among children below five years of age admitted at a Tertiary Hospital in Dar es Salaam, Tanzania.Annals of medicine · 2025Article
- When Coagulase-Negative Staphylococci Mislead: Transient Metabolic Acidosis in a Healthy Toddler.Cureus · 2025Article
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Authors and funding
10 authors.
Funding
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Abstract
backgroundCoagulase-negative staphylococci (CoNS) are the most commonly isolated bacteria from blood cultures and the most considered contaminants. We conducted a study to assess clinical and laboratory indicators predicting CoNS as a cause of bloodstream infections using two sets of blood cultures among under-five children in Dar es Salaam, Tanzania. In addition, we determined the antimicrobial susceptibility patterns of CoNS. MATERIALS AND
methodsThis cross-sectional study involved 246 children clinically diagnosed with bloodstream infections admitted to a tertiary hospital . Two sets of blood cultures were collected per patient. Blood samples were tested for microbial growth and antimicrobial susceptibility. Indicators independently predicting CoNS as a cause of bloodstream infection were calculated by binary logistic regression analysis, receiver operating characteristic (ROC) curve analysis to assess the diagnostic performance of predictors. A
resultsOf 246 patients, 100(40.7%) were positive blood cultures. CoNS were the most prevalent, isolated in 51(51.0%) blood cultures. Of 51 blood cultures with CoNS, 40(78.4%) were isolated in both blood culture bottles of a set and were regarded as causative of bloodstream infection,of this 34(85.0%) were methicillin resistance CoNS. Multivariate analysis identified tachycardia (aOR = 14.69, 95%CI 1.36-158.42,
conclusionsCoNS remains the most common bacteria causing bloodstream infections.
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