Evidence map›Paper›PMID 40377206›Full record

ArticleeLife2025

Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions.

Katarzyna Tutak, Izabela Broniarek, Andrzej Zielezinski, Daria Niewiadomska, Tomasz Skrzypczak, Anna Baud, Krzysztof Sobczak

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katarzyna TutakDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, Poznan, Poland.ORCID https://orcid.org/0000-0002-2801-9956
Izabela BroniarekDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, Poznan, Poland.
Andrzej ZielezinskiDepartment of Computational Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University Uniwersytetu Poznańskiego 6, Poznan, Poland.
Daria NiewiadomskaDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, Poznan, Poland.
Tomasz SkrzypczakCenter of Advanced Technology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, Poznan, Poland.
Anna BaudDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, Poznan, Poland.ORCID https://orcid.org/0000-0003-3710-5722
Krzysztof SobczakDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, Poznan, Poland.ORCID https://orcid.org/0000-0001-8352-9812

Funding

Adam Mickiewicz University Foundation Scholarship for the best PhD StudentsHorizon 2020 Framework Programme 101003385Initiative of Excellence-Research University at Adam Mickiewicz University, Poznan 140/04/POB2/0006Polish National Science Center 2019/35/D/NZ2/02158Polish National Science Center 2020/38/A/NZ3/00498
6 · The paper itself

Abstract

Expansion of CGG repeats (CGGexp) in the 5' untranslated region (5'UTR) of the

Indexed as

Fragile X Messenger Ribonucleoprotein 1Fragile X SyndromePeptidesProtein BiosynthesisRibosomal ProteinsAtaxiaFemaleHumansTremorFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1PeptidespolyglycineRibosomal Proteinscell biologyexpansion of triplet repeatsFMR1humannear-cognate start codonpolyglycineribosomal heterogeneityunstable CGG repeats

Identifiers

PMID40377206
PMCPMC12084008

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.