Evidence map›Paper›PMID 40377097›Full record

ArticleNucleic acids research2025

LitSense 2.0: AI-powered biomedical information retrieval with sentence and passage level knowledge discovery.

Lana Yeganova, Won Kim, Shubo Tian, Donald C Comeau, W John Wilbur, Zhiyong Lu

Abstract read
In one paragraph

Article in Nucleic acids research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lana YeganovaDivision of Intramural Research (DIR), National Library of Medicine (NLM), National Institutes of Health (NIH), MD 20894 Bethesda, United States.ORCID 0009-0006-0165-7161
Won KimDivision of Intramural Research (DIR), National Library of Medicine (NLM), National Institutes of Health (NIH), MD 20894 Bethesda, United States.
Shubo TianDivision of Intramural Research (DIR), National Library of Medicine (NLM), National Institutes of Health (NIH), MD 20894 Bethesda, United States.ORCID 0000-0001-6415-1439
Donald C ComeauDivision of Intramural Research (DIR), National Library of Medicine (NLM), National Institutes of Health (NIH), MD 20894 Bethesda, United States.
W John WilburDivision of Intramural Research (DIR), National Library of Medicine (NLM), National Institutes of Health (NIH), MD 20894 Bethesda, United States.
Zhiyong LuDivision of Intramural Research (DIR), National Library of Medicine (NLM), National Institutes of Health (NIH), MD 20894 Bethesda, United States.ORCID 0000-0001-9998-916X

Funding

NIH HHS
6 · The paper itself

Abstract

LitSense 2.0 (https://www.ncbi.nlm.nih.gov/research/litsense2/) is an advanced biomedical search system enhanced with dense vector semantic retrieval, designed for accessing literature on sentence and paragraph levels. It provides unified access to 38 million PubMed abstracts and 6.6 million full-length articles in the PubMed Central (PMC) Open Access subset, encompassing 1.4 billion sentences and ∼300 million paragraphs, and is updated weekly. Compared to PubMed and PMC, the primary platforms for biomedical information search, LitSense offers cross-platform functionality by searching seamlessly across both PubMed and PMC and returning relevant results at a more granular level. Building on the success of the original LitSense launched in 2018, LitSense 2.0 introduces two major enhancements. The first is the addition of paragraph-level search: users can now choose to search either against sentences or against paragraphs. The second is improved retrieval accuracy via a state-of-the-art biomedical text encoder, ensuring more reliable identification of relevant results across the entire biomedical literature.

Indexed as

Artificial IntelligenceInformation Storage and RetrievalKnowledge DiscoverySoftwareData MiningHumansPubMedSemantics

Identifiers

PMID40377097
PMCPMC12230651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.