Evidence map›Paper›PMID 40377028›Full record

ArticleACS chemical biology2025

Structural Insights into Spare-Tire DNA G-Quadruplex from the Human

Ines Burkhart, Vivien Rose McKenney, Julia Wirmer-Bartoschek, J Tassilo Grün, Alexander Heckel, Harald Schwalbe

Abstract read
In one paragraph

Article in ACS chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ines BurkhartInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, Max-von-Laue-Str. 7, Frankfurt/Main, Hesse 60438, Germany.
Vivien Rose McKenneyInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue-Str. 7, Frankfurt/Main, Hesse 60438, Germany.
Julia Wirmer-BartoschekInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, Max-von-Laue-Str. 7, Frankfurt/Main, Hesse 60438, Germany.
J Tassilo GrünInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, Max-von-Laue-Str. 7, Frankfurt/Main, Hesse 60438, Germany.
Alexander HeckelInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue-Str. 7, Frankfurt/Main, Hesse 60438, Germany.
Harald SchwalbeInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, Max-von-Laue-Str. 7, Frankfurt/Main, Hesse 60438, Germany.ORCID 0000-0001-5693-7909

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vascular endothelial growth factor (

Indexed as

DNAG-QuadruplexesPromoter Regions, GeneticVascular Endothelial Growth Factor ACircular DichroismHumansDNAVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID40377028
PMCPMC12186258

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.