ArticleFrontiers in neuroscience2025
An evaluation of distinct adeno-associated virus vector strategies for driving transgene expression in spinal inhibitory neurons of the rat.
Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Gene Therapy Tools for Diseases Caused by Mutations of the Mitochondrial Genome.International journal of molecular sciences · 2026Review
- Article
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6 authors.
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Abstract
The spinal cord dorsal horn (DH) is essential for processing and transmitting nociceptive information. Its neuronal subpopulations exhibit significant heterogeneity in morphology and intrinsic properties, forming complex circuits that remain only partially understood. Under physiological and pathological conditions, inhibitory interneurons in the DH are of particular interest. These neurons modulate and refine pain-related signals entering the central nervous system. The ability to selectively target these inhibitory interneurons is key to investigating the underlying circuitry and mechanisms of pain processing, as well as to understand the specific role of inhibitory signaling within these processes. We employed a viral vector approach to deliver a fluorescent reporter protein specifically to inhibitory interneurons in the rat spinal cord. Using adeno-associated virus (AAV) vectors designed to express enhanced green fluorescent protein (EGFP) under the control of various promoters, we targeted distinct subtypes of spinal inhibitory interneurons. Through immunostaining,
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