Evidence map›Paper›PMID 40376382›Full record

ArticleCureus2025

Primary Localized Cutaneous Amyloidosis Presenting With Tumor-Like Swelling in the Lower Extremity: A Rare Presentation.

Ahmed Almukhlifi, Ayman Ibrahim, Ahmed Hazazzi, Noorah Almadani

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ahmed AlmukhlifiDepartment of Medicine, Ministry of National Guard Health Affairs, Riyadh, SAU.
Ayman IbrahimDepartment of Hematology, King Abdulaziz Medical City, Riyadh, SAU.
Ahmed HazazziDepartment of Internal Medicine, Ministry of National Guard, Riyadh, SAU.
Noorah AlmadaniDepartment of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloidosis consists of a spectrum of disease ranging from primary localized forms to secondary forms due to systemic disease. Amyloidoma, a variant of localized amyloidosis, is the least frequent manifestation of tissue amyloid deposition, which can be either amyloid A (AA) or amyloid light-chain (AL) type. Soft tissue amyloidoma is uncommon and mostly affects the abdomen and mediastinum and rarely affects the extremities. We present a middle-aged woman who developed a tumor-like swelling in the extremity, in which comprehensive investigations revealed features of primary amyloidosis with no evidence of internal involvement, representing a rare presentation.

Indexed as

al kappa-type amyloidosisamyloidomaamyloidosisextremitynodular amyloidosisprimary localized cutaneous amyloidosissoft tissue swellingtumor

Identifiers

PMID40376382
PMCPMC12079143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.