Evidence map›Paper›PMID 40376351›Full record

ArticleCureus2025

Gouty Tophus in the Small Bowel Mimicking a Calcifying Mesenteric Mass.

Vanessa Diller, Daniel Perez, Alexander Harms, Luca M Tavernar, Sven Petersen

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vanessa DillerGeneral and Visceral Surgery, Asklepios Hospital Altona, Hamburg, DEU.
Daniel PerezGeneral and Visceral Surgery, Asklepios Hospital Altona, Hamburg, DEU.
Alexander HarmsPathology, MVZ HPH Institute for Pathology and Hematopathology, Hamburg, DEU.
Luca M TavernarPathology, MVZ HPH Institute for Pathology and Hematopathology, Hamburg, DEU.
Sven PetersenGeneral and Visceral Surgery, Asklepios Hospital Altona, Hamburg, DEU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gout is a common metabolic disorder caused by hyperuricemia, which results in the deposition of monosodium urate crystals in various parts of the body. In the present case, a large gout tophus was detected based on gout disease. Although gouty tophi might occur in many locations during a long-standing gout disease, the vast majority are located in the articular tissue. An 80-year-old female patient was admitted to the emergency room complaining of persistent nausea and vomiting for two days. In addition, she reported abdominal pain and cramps that she had not experienced before. A CT scan revealed a large calcified mesenteric mass in the right side of the abdomen. The patient underwent surgery and removal of the mesenteric mass including 55-cm jejunal resection. Histologically, sections showed a capsule-like boundary of varying widths, mostly cell-poor lesions, as well as siderophages and strong lymphatic infiltrate at the margins, corresponding to residual lymph node tissue. In the periphery of the lesion, brace-shaped dystrophic calcifications completed the histological image of a gouty tophus. In this case report, we describe an extremely rare case of a mass in the area of the small intestine mesentery caused by monosodium urate crystals. Even if patients do not present with articular manifestation of gout, deposition in other tissues is possible and presents a risk factor for the development of diseases. For patients with unclear abdominal masses suffering from hyperuricemia, despite being rare, a gout tophus should be thought of.

Indexed as

chronic goutgout crystalgout diseasesmall bowel resectionsurgery

Identifiers

PMID40376351
PMCPMC12079704

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.