ArticleCureus2025
Vaginal Microbiota in Women With Spontaneous Preterm Labor Compared to Spontaneous Term Labor: A Cross-Sectional Analytical Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Dynamic changes in the pregnancy microbiome and their role in preterm birth.Frontiers in cellular and infection microbiology · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm birth is the second leading cause of neonatal morbidity and mortality. This study aimed to determine if there were differences in the microbiota between women experiencing preterm labor and those with full-term pregnancies. Additionally, we aimed to identify the vaginal microorganisms present and their antibiotic sensitivities in women undergoing spontaneous preterm labor.
methodsWomen with a spontaneous onset of labor were recruited for the study. Those with spontaneous term labor were classified as Group A, while those with preterm labor were classified as Group B. Three high vaginal swabs were collected from the posterior fornix using a sterile swab and sent to the Microbiology Department for Gram staining, culture and sensitivity testing, and polymerase chain reaction analysis.
resultsThe frequency of vaginal infection is more among women in spontaneous preterm labor than those in spontaneous term labor. Socioeconomic status and women with a previous history of preterm labor were found to be at high risk for preterm labor. The most common organism belongs to Gram-negative bacilli and is sensitive to third-generation cephalosporins.
conclusionThe study suggests that vaginal infections may increase the risk of preterm labor, with gram-negative bacilli commonly identified and mostly sensitive to third-generation cephalosporins. Routine screening for asymptomatic genital infections in antenatal women is recommended, regardless of preterm labor risk, as early identification and treatment could help prevent preterm labor.
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