Evidence map›Paper›PMID 40376296›Full record

ArticleHealth science reports2025

Association Between Thyroid Hormone Levels and Disease Prognosis in Guillain-Barré Syndrome: A Retrospective Study.

Yangrongzhuo Huang, Yuhan Li, Hailing Zhou, Juan Tang

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yangrongzhuo HuangDepartment of Neurology The First Affiliated Hospital of Shihezi University Shihezi China.ORCID 0009-0000-4770-5110
Yuhan LiDepartment of Neurology The First Affiliated Hospital of Shihezi University Shihezi China.
Hailing ZhouDepartment of Neurology The First Affiliated Hospital of Shihezi University Shihezi China.
Juan TangDepartment of Neurology The First Affiliated Hospital of Shihezi University Shihezi China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction/Aims: Guillain-Barré syndrome (GBS) is an immune-mediated neuropathy characterized by progressive sensory and motor dysfunction, often accompanied by abnormal inflammatory markers and thyroid hormone levels. However, the underlying mechanisms and their impact on prognosis remain incompletely understood. This study aimed to investigate the correlation between thyroid hormone levels and prognosis in GBS, analyze the association between thyroid hormone levels and inflammatory markers, and further explore potential mechanisms and clinical implications. Methods: We retrospectively analyzed clinical data from 182 GBS patients admitted to the First Affiliated Hospital of Shihezi University between December 2019 and April 2024. Data included thyroid hormone levels and inflammatory markers (e.g., neutrophils, leukocytes). Functional status was assessed using the Hughes Functional Grading Scale (HFGS) within 3 months post-discharge. Patients were stratified into two groups: HFGS score < 3 (good prognosis group, Results: Reduced FT4 and T4 levels were significantly associated with poor prognosis in GBS patients ( Conclusion: This study suggests that low FT4 and T4 levels are independent risk factors for poor prognosis in GBS patients, with thyroid hormone levels exhibiting certain associations with inflammatory markers.

Indexed as

clinical characteristicsfree thyroxineGuillain–Barré syndromeinflammatory markersprognosisthyroid hormone levelsthyroxine

Identifiers

PMID40376296
PMCPMC12079770

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