ArticleFrontiers in public health2025
Quantifying the temporal trends of the combined effect of temperature and relative humidity on hand, foot, and mouth disease in Yunnan, China.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hand, foot, and mouth disease (HFMD) poses a significant risk to children. While most studies focus on the individual effects of temperature or relative humidity, the combined effect of these factors and their temporal variations remain unclear. Understanding these effects is essential for designing effective public health interventions. Methods: Using daily meteorological and HFMD case data collected from 2010 to 2019 in 16 cities in Yunnan Province, China, we compared three composite indices (Humidex, heat index, and temperature-humidity index) to identify the indices that best captured the combined effect of temperature and humidity on HFMD risk. An extended time-varying distributed lag nonlinear model (DLNM) was used to examine how these effects shifted over time across population subgroups. Relative risk (RR) values at the 1%, 25%, 75%, and 99% quantiles were extracted to represent effects at extremely, moderately low, moderately, and extremely high levels. Results: The THI Conclusion: The THI
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