Evidence map›Paper›PMID 40376018›Full record

ReviewEndoscopy international open2025

Biliary stent insertion after stone clearance in patients awaiting cholecystectomy: Systematic review and meta-analysis.

Marco Valvano, Daniele Balducci, Antonio Vinci, Andrea Ghezzi, Shirin Djahandideh, Stefano Fabiani, Gianpiero Stefanelli, Silvia Buccilli, Amedeo Montale, Filippo Antonini and 2 more

Abstract readReview
In one paragraph

Review in Endoscopy international open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marco ValvanoDepartment of Health Sciences, University of L'Aquila Department of Health Sciences, L'Aquila, Italy.ORCID 0000-0002-2201-6279
Daniele BalducciUniversità Politecnica delle Marche, Ancona, Italy.
Antonio VinciUniversity of Rome Tor Vergata, Roma, Italy.
Andrea GhezziEnte Ospedaliero Ospedali Galliera, Genova, Italy.
Shirin DjahandidehEnte Ospedaliero Ospedali Galliera, Genova, Italy.
Stefano FabianiPescara Hospital, Pescara, Italy.
Gianpiero StefanelliEnte Ospedaliero Ospedali Galliera, Genova, Italy.
Silvia BuccilliEnte Ospedaliero Ospedali Galliera, Genova, Italy.
Amedeo MontaleEnte Ospedaliero Ospedali Galliera, Genova, Italy.
Filippo AntoniniGastroenterology and Digestive Endoscopy, Augusto Murri Hospital, Fermo, Italy.ORCID 0000-0001-5453-3310
Luca MaroniUniversità Politecnica delle Marche, Ancona, Italy.
Chiara CampanaleEnte Ospedaliero Ospedali Galliera, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and study aims: Laparoscopic cholecystectomy is the standard treatment for patients with cholecystitis or gallbladder stones after common bile duct (CBD) clearance. According to the sequential strategy, cholecystectomy should be performed within 2 weeks after CDB clearance with endoscopic retrograde cholangiopancreatography (ERCP). However, in real-life experience, the average waiting time is 60 to 180 days. We aimed to evaluate the clinical rationale for prophylactic stent placement in CBD to prevent recurrent biliary events. Patients and methods: This systematic review and meta-analysis was performed following a protocol designed a priori (PROSPERO: CRD42024564804; July 13, 2024). All published studies involving patients who had undergone ERCP for CBDs and who were awaiting cholecystectomy were included. Results: At the end of the revision process, four full texts including 755 patients were included in the meta-analysis. The odds ratio (OR) for symptom recurrence in patients awaiting cholecystectomy was 0.74 (95% confidence interval [CI] 0.30-1.79; I Conclusions: This meta-analysis showed no benefit for stent insertion after bile duct clearance in patients scheduled for delayed cholecystectomy. Further randomized controlled trials with bigger cohorts are needed to assess any benefit for this procedure, which in the meantime, cannot be recommended.

Indexed as

CholangioscopyERC topicsPancreatobiliary (ERCP/PTCD)Stones

Identifiers

PMID40376018
PMCPMC12080521

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.