Evidence map›Paper›PMID 40375991›Full record

ArticleFrontiers in immunology2025

Efficacy of Telitacicept in treating IgA vasculitis nephritis: a two-case report.

Shuang-Xi Li, Rui-Kang Hu, De-Liang Kong, Jing Xu, Qi Bian, Zhi-Yong Guo, Xiao-Bin Mei

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. [Research progress on the application of telitacicept in rheumatism and autoimmune diseases].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuang-Xi Li *Department of Nephrology, Changhai Hospital, The Naval Medical University, Shanghai, China.
Rui-Kang Hu *Medical School of Chinese People's Liberation Army (PLA), Beijing, China.
De-Liang KongDepartment of Nephrology, Changhai Hospital, The Naval Medical University, Shanghai, China.
Jing XuDepartment of Nephrology, Changhai Hospital, The Naval Medical University, Shanghai, China.
Qi BianDepartment of Nephrology, Changhai Hospital, The Naval Medical University, Shanghai, China.
Zhi-Yong GuoDepartment of Nephrology, Changhai Hospital, The Naval Medical University, Shanghai, China.
Xiao-Bin MeiDepartment of Nephrology, Changhai Hospital, The Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telitacicept, a B lymphocyte stimulator/A proliferation-inducing ligand dual-target fusion protein, mainly used for IgA nephropathy and systemic lupus erythematosus. We present two cases where adult patients with IgA vasculitis (IgAV) nephritis were successfully treated with Telitacicept, experienced no adverse reactions during the follow-up. Therefore, Telitacicept represents a promising additional treatment option for patients suffering from IgA vasculitis (IgAV).

Indexed as

Glomerulonephritis, IGAIgA VasculitisImmunoglobulin ARecombinant Fusion ProteinsAdultHumansTreatment OutcomeImmunoglobulin ARecombinant Fusion ProteinstelitaciceptAPRILBAFFHenoch-Schönlein purpura (HSP)IgA vasculitisTelitacicept

Identifiers

PMID40375991
PMCPMC12078309

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.