Evidence map›Paper›PMID 40375885›Full record

ArticleRheumatology advances in practice2025

External validation of the polymyalgia rheumatica impact scale: a prospective cohort study.

Lien Moreel, Michaël Doumen, Albrecht Betrains, Ellen De Langhe, Daniel Blockmans, Steven Vanderschueren

Abstract read
In one paragraph

Article in Rheumatology advances in practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lien MoreelDepartment of General Internal Medicine, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-7613-4801
Michaël DoumenDepartment of Rheumatology, UZ Leuven, Leuven, Belgium.
Albrecht BetrainsDepartment of General Internal Medicine, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-7526-5001
Ellen De LangheDepartment of Rheumatology, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-4045-2146
Daniel BlockmansDepartment of General Internal Medicine, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-9783-1780
Steven VanderschuerenDepartment of General Internal Medicine, UZ Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To externally validate the PMR impact scale (PMR-IS). Methods: We conducted a prospective cohort study at the University Hospitals Leuven, Leuven, Belgium. Recently diagnosed PMR patients were included between July 2022 and December 2023 and followed until 1 year after diagnosis. All patients completed the PMR-IS, HAQ Disability Index, 36-item Short Form and a visual analogue scale for pain at every visit. Internal consistency, floor and ceiling effects, construct validity, responsiveness and discriminatory power for detecting relapse on the PMR-IS were assessed. Results: Fifty-five PMR patients (mean age 71 years, 47% female) were included, who had a total of 246 visits. Internal consistency, construct validity and responsiveness met the quality criteria for the symptoms, function and emotional and psychological well-being subdomains. The internal consistency of the glucocorticoid side effects subdomain was insufficient and only one of the three hypotheses for construct validity were met. The function and emotional and psychological well-being subdomains showed a floor effect, while no ceiling effect was observed. The symptoms, function and emotional and psychological well-being subdomains had a good discriminatory power for detecting relapse [area under the curve (AUC) 0.89, 0.86 and 0.72, respectively], but the PMR activity score performed better (AUC 0.94, Conclusion: This study validates the good measurement properties of the symptoms, function and emotional and psychological well-being subdomains of the PMR-IS. In contrast, the glucocorticoid side effects subdomain did not show adequate internal consistency and construct validity, necessitating further validation and possibly refinement of its items prior to application in clinical trials or daily practice.

Indexed as

patient-reported outcome measurePMRPMR impact scalepolymyalgia rheumatica

Identifiers

PMID40375885
PMCPMC12080742

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.