Evidence map›Paper›PMID 40375851›Full record

ArticleJournal of clinical and experimental dentistry2025

Histological effect of fluoride varnishes on teeth with caries in the white spot phase: An

Margot Margarita Gutiérrez-Ilave, Rocío Del Pilar Ríos-León, Antonia Castro-Rodríguez, María Rosario Calixto-Cotos

Abstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Margot Margarita Gutiérrez-IlaveDDS. MSc., Professor of the Department of Preventive and Social Stomatology, Faculty of Dentistry, Universidad Nacional Mayor de San Marcos. Lima, Perú.
Rocío Del Pilar Ríos-LeónDDS., Master Student in Dentistry, Faculty of Dentistry, Universidad Nacional Mayor de San Marcos. Lima, Perú.
Antonia Castro-RodríguezDDS. MSc., Professor of the Department of Preventive and Social Stomatology, Faculty of Dentistry, Universidad Nacional Mayor de San Marcos. Lima, Perú.
María Rosario Calixto-CotosDDS. MSc., Professor of the Department of Analytical Chemistry. Faculty of chemistry and chemical engineering. Universidad Nacional Mayor de San Marcos. Lima, Perú.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to compare the histological remineralization effects of two fluoride varnishes on artificially produced caries lesions in young permanent teeth. Material and Methods: Twenty longitudinal sections of premolars with artificially produced white spot lesions and evaluated with a polarised light microscope. The sample consisted of 20 tooth fragments, which were divided and assigned to two groups: The first group with application of Clinpro TM White Varnish (20 tooth sections) and the second, with MI Varnish TM (20 tooth sections) subjected for 6 days to conditions similar to the oral cavity. The sections were then re-evaluated by calculating the lesion depth and remineralization area (Image J software). Student' s t-test was used to analyse the data. Results: MI Varnish TM fluoride varnish achieved a greater remineralization area than Clinpro TM White Varnish (838042.6±140359.3 μm2 and 678313.8±137265.7μm2, respectively), with a statistically significant difference ( Conclusions: MI Varnish TM had a better effect than Clinpro TM White Varnish in remineralizing lesions, in vitro, in the enamel of young permanent teeth with caries in the white-stained phase.

Identifiers

PMID40375851
PMCPMC12077836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.