Evidence map›Paper›PMID 40375847›Full record

ArticleJournal of clinical and experimental dentistry2025

Comparative analysis of postoperative pain with glycolic acid vs. ethylenediaminetetraacetic acid in endodontic treatment: A randomized clinical trial.

Bruna Tozzati Lago, Doglas Cecchin, Ulysses Lenz, Carlo Theodoro Raymundi Lago, Ana Paula Farina, Matheus Albino Souza, João Paulo de Carli, Yuri Dal Bello

Abstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bruna Tozzati LagoPostgraduate Student, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
Doglas CecchinDepartment of Restorative Dentistry, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
Ulysses LenzPostgraduate Student, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
Carlo Theodoro Raymundi LagoPostgraduate Student, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
Ana Paula FarinaDepartment of Restorative Dentistry, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
Matheus Albino SouzaDepartment of Restorative Dentistry, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
João Paulo de CarliDepartment of Restorative Dentistry, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
Yuri Dal BelloDepartment of Restorative Dentistry, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to evaluate pain and analgesic intake after endodontic treatment using glycolic acid (GA) or ethylenediaminetetraacetic acid (EDTA) as the final irrigating solution. Material and Methods: One hundred fifty patients were randomly assigned to two groups for smear layer removal: 17% GA or 17% EDTA. Postoperative pain was assessed at 24, 48 hours and 7 days. The need for analgesic intake was recorded. Descriptive analysis was performed to assess demographics (Student t, Chi-square and Fisher tests) and study outcomes (Mann Whitney, Friedman and Nemenyi) ( Results: Postoperative pain occurred in 52% of the cases. In the 24-hour period, GA had a significantly lower pain score ( Conclusions: GA is associated with less postoperative pain at 24 hours compared to EDTA. No statistically significant difference was observed at 48 hours and 7 days.

Identifiers

PMID40375847
PMCPMC12077834

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.