Evidence map›Paper›PMID 40375767›Full record

ReviewEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2025

Leaflet modification techniques to mitigate coronary obstruction risk during transcatheter aortic valve implantation.

Sunny Goel, Richard Tanner, Kwong-Yue Eric Chan, Jaffar M Khan, Manish Vinayak, Stamatios Lerakis, Lucy M Safi, Sahil Khera, Parasuram Krishnamoorthy, Annapoorna S Kini and 3 more

Abstract readReview
In one paragraph

Review in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sunny GoelDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Richard TannerDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kwong-Yue Eric ChanCardiology Division, Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Jaffar M KhanSt. Francis Hospital and Heart Center, Roslyn, NY, USA.
Manish VinayakDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stamatios LerakisDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lucy M SafiDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sahil KheraDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Parasuram KrishnamoorthyDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Annapoorna S KiniDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Samin K SharmaDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
George D DangasDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gilbert H L TangDivision of Cardiology, The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary obstruction is a rare but serious complication during transcatheter aortic valve implantation (TAVI), particularly in valve-in-valve procedures, which is associated with high mortality. This review explores various leaflet modification techniques designed to mitigate this risk. Among the most studied methods is Bioprosthetic or native Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA), which uses transcatheter electrosurgery to lacerate the aortic valve leaflet and maintain coronary perfusion. Other promising techniques include ShortCut, a mechanical leaflet splitting device, and Undermining Iatrogenic Coronary Obstruction with Radiofrequency Needle (UNICORN), which utilises radiofrequency energy to achieve leaflet laceration. These approaches differ in their procedural complexity, equipment requirements, and clinical outcomes. Each technique's efficacy in preventing coronary obstruction is discussed, alongside the potential complications and the procedural challenges encountered in both native aortic valve and valve-in-valve settings. This review also highlights the importance of careful patient selection, advanced imaging techniques, and the need for further research to optimise these strategies.

Indexed as

Aortic ValveAortic Valve StenosisCoronary OcclusionTranscatheter Aortic Valve ReplacementBioprosthesisElectrosurgeryHeart Valve ProsthesisHumansIatrogenic DiseaseRisk FactorsTreatment Outcome

Identifiers

PMID40375767
PMCPMC12063549

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.