ArticleJournal of surgical oncology2025
Frailty Is an Independent Marker of Post-Operative Mortality Following Colorectal Cancer Resection Surgery in Older Adults.
Article in Journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- "Having surgery is necessary" - a qualitative analysis of the experiences of frail older adults treated with, and recovering from colorectal cancer surgery.BMC geriatrics · 2026Trial
- Frailty and colon cancer surgery: Accounting for survivorship bias in patient-reported outcomes.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Long-Term Functional Outcomes After Prehabilitation in Frail Older Adults Undergoing Colorectal Cancer Surgery: A One-Year Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Mild to moderate frailty among older adults does not affect long-term quality of life or functional outcomes after colon cancer surgery.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Observational
- Outcomes Following Colorectal Cancer Resection in Elderly Patients.Current oncology (Toronto, Ont.) · 2025Article
- Decoding the Effect of Frailty vs. Physiologic Age in Octogenarian and Nonagenarian Colectomy Outcomes for Colon Cancer.Journal of clinical medicine · 2025Article
- Surgery Reduces Cancer-specific Death in Elderly Right-Sided Colon Cancer: A SEER-Based Competing-Risk Analysis.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
BACKGROUND AND
objectivesFrailty is a prognostic factor of post-operative death and complications following colorectal cancer surgery. Frailty assessment is not routinely performed, hence, the prevalence is unknown. The aim of this study was to establish the presence of frailty in patients aged ≥ 70 years, and to analyse differences in post-operative outcome comparing frail and non-frail elderly patients.
methodData of patients aged ≥ 70 years who underwent colorectal cancer surgery during 2016-2020 were retrospectively obtained from the Swedish Colorectal Cancer Registry. A cohort of 500 patients was assessed for frailty using the Clinical Frailty Scale (CFS-9). Post-operative mortality rates, complications, readmissions, and length of stay (LOS) were compared between frail and non-frail patients.
resultsThe prevalence of frailty (CFS-9 score ≥ 4) was 56%. The 90-day mortality rate was higher in frail patients (OR 4.97 [95% CI 1.06-23.28], p 0.042), as well as 1-year mortality (OR 4.39 [95% CI 1.86-10.34], p 0.0007). Frail patients had longer post-operative LOS (7.63 vs. 11.0 days, p < 0.001), were more often treated in ICU and more often discharged to a nursing home.
conclusionFrailty is a common condition in patients ≥ 70 years and a significant risk factor of post-operative mortality and morbidity.
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