Evidence map›Paper›PMID 40375218›Full record

Trial reportBMC oral health2025

Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial.

Liping Dong, Jianshe Li, Peng Xue, Suixin Hu, Chen Xu, Lin Wang, Liu Liu, Qiang Luo, Huixia He, Fei Chen

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liping Dong *Department of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China.
Jianshe Li *Outpatient Department of TPL, Southern Medical Branch of PLA General Hospital, No.28 Wanshou Road, Haidian District, Beijing, 100858, China.
Peng Xue *Department of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China.
Suixin HuDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China.
Chen XuDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China.
Lin WangDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China.
Liu LiuDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China.
Qiang LuoDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China. pkuhawking@foxmail.com.
Huixia HeDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China. xiahuih-203@163.com.
Fei ChenDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China. czjch1209@qq.com.

Funding

the 2023 Hospital-Level New Service Projects of Chinese PLA General Hospital 2023-2-4the Youth Independent Innovation Science Fund Project of Chinese PLA General Hospital 22QNFC037
6 · The paper itself

Abstract

backgroundTo evaluate the clinical efficacy and outcomes of C-Root SP bioceramic-based sealers combined with different obturation techniques in nonsurgical root canal treatment for older patients.

methodsThis prospective, single-center, single-blind, parallel, randomized clinical trial included 240 patients aged ≥ 60 years. Patients were randomly divided into four treatment groups. Group A: C-Root SP combined with single-cone (SC); Group B: C-Root SP combined with warm vertical compaction (WVC); Group C: C-Root SP combined with cold lateral condensation (CLC); Group D: iRoot SP combined with SC (Control). All teeth were subjected to root canal filling using the corresponding methods 7-10 days after root canal preparation and medication. The duration of obturation was recorded. Periapical radiographs were obtained immediately after obturation to determine the length of root canal filling, and postoperative pain on days 1, 2, and 7 was documented. The treatment outcomes based on clinical signs and symptoms as well as periapical index (PAI) were analyzed at 1 year postoperatively.

resultsGroups A and D exhibited significantly higher filling efficiency than groups B and C (P < 0.001). No significant differences were observed in the length of obturation between the groups (P > 0.05). Postoperative pain decreased over time in all groups, with group A showing significantly lower pain rates on day 1 than the other groups (P < 0.05). After 1 year, all groups exhibited considerable reductions in the PAI scores, with success rates ranging from 91.23 to 94.83%; however, no significant differences were observed between them (P > 0.05).

conclusionsC-Root SP combined with different obturation techniques yielded similar outcomes to iRoot SP combined with the SC technique in terms of filling length, success rate, and changes in PAI scores. The SC technique demonstrated significant advantages in terms of clinical efficiency and may reduce early postoperative pain when combined with C-Root SP.

trial registrationThe study was retrospectively registered in chictr.org.cn with the identifier: ChiCTR2400092580 on 11/19/2024.

Indexed as

Root Canal Filling MaterialsRoot Canal ObturationRoot Canal TherapyAgedCeramicsFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative PainProspective StudiesRoot Canal PreparationSingle-Blind MethodTreatment OutcomeRoot Canal Filling MaterialsBioceramic-based sealersClinical trialEndodontic outcomesObturation techniquePostoperative pain

Identifiers

PMID40375218
PMCPMC12082915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.