SynthesisBMC pediatrics2025
The near-infrared spectroscopy to evaluate neonatal improvement after transfusion: a systematic review and meta-analysis.
Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between packed red blood cell transfusion and clinical deterioration in neonatal necrotizing enterocolitis: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- The Effect of Liberal versus Restrictive Haemoglobin Thresholds on Cerebral Tissue Oxygenation in Preterm Infants: A Systematic Review and Meta-Analysis.Neonatology · 2026Pooled it
- Pulse Oximetry Histogram Profiles Before and After Red Blood Cell Transfusion in Very Preterm Infants: A Prospective Observational Cohort.Children (Basel, Switzerland) · 2026Article
- Changes in central and peripheral hemodynamic parameters during blood donation.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundAnemia of prematurity (AOP) is a common issue in neonatal intensive care units (NICUs) globally, associated with significant morbidity and mortality. Near-infrared spectroscopy (NIRS) has emerged as a noninvasive, real-time monitoring tool to assess tissue oxygenation and blood flow, potentially providing valuable insights into the impact of red blood cell transfusions in preterm infants with anemia. This study aimed to evaluate the effectiveness of NIRS in assessing improvements in preterm infants after red blood cell transfusions.
methodsThis study followed a systematic review and meta-analysis design, adhering to the Cochrane Handbook for Systematic Reviews of Interventions and PRISMA guidelines. No geographic or temporal restrictions were imposed during the search. The final included studies spanned 2008-2017 and originated from four countries. A total of 214 articles were initially identified, and nine prospective observational studies were included in the final analysis. These studies focused on preterm infants diagnosed with anemia who required red blood cell transfusion therapy. The sample sizes in these studies ranged from 10 to 35 infants. The primary outcome was the changes in NIRS readings before and after transfusion. The secondary outcomes included changes in heart rate (HR), saturation of pulse oxygen (SPO
resultsMeta-analysis demonstrated significant post-transfusion increases in CrSO
conclusionsThe findings suggest that NIRS is a reliable tool for assessing the impact of red blood cell transfusions in preterm infants.
trial registrationPROSPERO (ID: CRD42024596069).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.