Evidence map›Paper›PMID 40375121›Full record

ArticleBMC plant biology2025

Characterization and expression of the wall-associated kinase/wall-associated kinase-like (WAK/WAKL) family in response to Botrytis cinerea infection in strawberry (Fragaria×ananassa).

Chenyang Xu, Zhimin He, Xiaoru Kang, Yanwei Zhao, Qingqing Peng, Min Wen, Jiaqi Yan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenyang Xu *College of Horticulture, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193, PR China.
Zhimin He *College of Horticulture, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193, PR China.
Xiaoru KangCollege of Horticulture, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193, PR China.
Yanwei ZhaoCollege of Horticulture, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193, PR China.
Qingqing PengCollege of Horticulture, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193, PR China.
Min WenCollege of Horticulture, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193, PR China.
Jiaqi YanCollege of Horticulture, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193, PR China. yanjiaqi@cau.edu.cn.

Funding

National Natural Science Foundation of China 32102038
6 · The paper itself

Abstract

backgroundGray mold caused by Botrytis cinerea is a major threat to the production of strawberry. An increasing number of studies have reported that wall-associated kinase/wall-associated kinase-like (WAK/WAKL) played an important role in the recognition of oligogalacturonic acids (OGs) and the induction of plant defense, but there have been no systematic studies of FaWAK/FaWAKL in strawberry.

resultsIn this study, we identified 167 FaWAK/FaWAKL gene family members within the strawberry (Fragaria×ananassa) genome. The phylogenetic analysis showed the FaWAK/FaWAKL gene family has been divided into five groups, and they were unevenly distributed on 46 chromosomes. An analysis of the cis-regulatory elements suggested the FaWAK/FaWAKL gene family was more sensitive to abscisic acid and methyl jasmonate. A total of 36 FaWAK/FaWAKL genes were activated by B. cinerea according to an RNA-seq analysis, and 8 of them strongly responded to B. cinerea and exogenous treatment with OGs, particularly FaWAK35. Transient overexpression of FaWAK35 increased the strawberry resistance to B. cinerea.

conclusionThis study conducted a comprehensive analysis of FaWAK/FaWAKL and provides foundational insights for further exploration of FaWAK/FaWAKL genes in strawberry resistance to B. cinerea.

Indexed as

BotrytisFragariaPlant DiseasesPlant ProteinsProtein KinasesDisease ResistanceGene Expression Regulation, PlantMultigene FamilyPhylogenyPlant ProteinsProtein KinasesBotrytis cinereaExpression analysisFragaria×ananassaOligogalacturonic acidsPlant-pathogen interactionWAK/WAKL

Identifiers

PMID40375121
PMCPMC12079969

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.