Evidence map›Paper›PMID 40375103›Full record

ArticleBMC geriatrics2025

Mediating role of frailty/pre-frailty on the association between exercise participation and traffic crashes among Japanese community-dwelling older drivers.

Jue Liu, Yuya Fujii, Keisuke Fujii, Jaehoon Seol, Koki Nagata, Tomohiro Okura

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Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jue LiuDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai, 200-040, China. susanliujue@gmail.com.
Yuya FujiiPhysical Fitness Research Institute, Meiji Yasuda Life Foundation of Health and Welfare, 150 Tobuki, Hachioji, Tokyo, 192-0001, Japan.
Keisuke FujiiDepartment of Rehabilitation Occupational Therapy Course, Faculty of Health Science, Suzuka University of Medical Science, 1001-1 Kishioka, Suzuka, Mie, 510-0293, Japan.
Jaehoon SeolInstitute of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8574, Japan.
Koki NagataDepartment of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.
Tomohiro OkuraInstitute of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8574, Japan.

Funding

Grant-in-Aid for Japan Society for the Promotion of Science Fellows 19J14505the Ministry of Education, Culture, Sports, Science and Technology of Japan Grant-in-Aid for Young Scientist (18K13035)
6 · The paper itself

Abstract

backgroundDriving is essential for maintaining independence. This study aimed to assess the mediating role of frailty status in the association between exercise participation and traffic crashes among Japanese community-dwelling older drivers.

methodsThis 2-year longitudinal study included data of 3,934 Japanese community-dwelling older drivers aged ≥ 65 years in Kasama City who did not require long-term care and participated in a postal survey in 2019 and 2021 at baseline and follow-up, respectively. The participants who exercised at least one-three times per month at baseline were classified as exercisers. Frailty status was assessed using the seven-domain Kihon Checklist. A self-reported history of traffic crashes was collected during the follow-up survey. The effect of exercise participation on traffic crash involvement was analyzed using logistic regression after adjusting for covariates. Mediation analyses were performed to determine the mediating effects of frailty status.

resultsA total of 357 (23.7%) and 1,147 (76.3%) older drivers were classified as exercisers and non-exercisers, respectively. Logistic regression analyses showed that exercise participation significantly reduced the risk of traffic crash involvement at follow-up (odds ratio [OR] = 0.586; 95% confidence interval [CI], 0.359-0.956) and was significantly associated with a lower risk of frailty/pre-frailty (OR = 0.479; 95% CI, 0.372-0.617). Although there was no significant association between exercise participation and traffic crash involvement at follow-up (OR = 0.631; 95% CI, 0.384-1.037), frailty/pre-frailty was associated with a significantly higher risk of traffic crash involvement compared with robustness (OR = 1.649; 95% CI, 1.061-2.563). The Sobel test revealed that frailty/pre-frailty mediated the association between exercise participation and traffic crash involvement at follow-up (p =.01). Additionally, among the seven domains of the Kihon Checklist, the physical domain mediated the association between exercise participation and traffic crash involvement at follow-up (p =.01).

conclusionsExercise participation could significantly lower the risk of traffic crashes, with frailty/pre-frailty acting as a mediating factor. Our findings indicated that managing frailty is crucial for both public health and crash prevention, emphasizing the need for promoting these measures among older drivers.

Indexed as

Accidents, TrafficAutomobile DrivingExerciseFrail ElderlyFrailtyIndependent LivingAgedAged, 80 and overEast Asian PeopleFemaleHumansJapanLongitudinal StudiesMaleExercise participationFrailty statusOlder driverTraffic crash

Identifiers

PMID40375103
PMCPMC12079984

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.