ArticleScientific reports2025
Antiparasitic efficacy of geraniol from Apiaceae family in scabies treatment.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
Sarcoptic mange, commonly known as scabies, is a highly contagious skin condition caused by the burrowing mite Sarcoptes scabiei (Astigmata: Sarcoptinae). This parasitic disease significantly impacts livestock and human health, particularly in underserved regions. Current treatments rely on synthetic acaricides like permethrin and ivermectin, which suffer from limitations such as toxicity, resistance development, and environmental contamination. Essential oils from Apiaceae plants represent a promising natural alternative. This study reviewed 122 volatile constituents from Apiaceae plants and conducted comprehensive in silico analyses to identify potential antiparasitic agents. Geraniol emerged as a potent acaricidal candidate due to its strong binding affinity to acetylcholinesterase (AChE) (docking score: - 7.85 kcal/mol). In vitro testing revealed geraniol achieved a 100% mite mortality rate at concentrations as low as 6.25% within 15 min (LT
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